SPHINGOMYELINASE
Synonym(s):Sphingomyelin choline phosphohydrolase;Sphingomyelin phosphodiesterase
- CAS NO.：9031-54-3
- Molecular Weight: 0
- MDL number: MFCD00132362
- EINECS: 232-869-9
- Update Date: 2026-05-28 02:17:02
What is SPHINGOMYELINASE?
The Uses of SPHINGOMYELINASE
sphingomyelinase is a fluid that can enhance the skin’s moistureretention properties.
The Uses of SPHINGOMYELINASE
Sphingomyelinase from Bacillus cereus has been used:
- in the measurement of membrane capacitance in brain slices
- for testing and confirming its silkworm-killing activity
- in enzyme activity assay and for elucidating its effect on hydrolysis of sphingomyelin in complex lipid mixtures
The Uses of SPHINGOMYELINASE
Sphingomyelinase from Staphylococcus aureus has been used to:
- induce neurotoxicity in rat cortical cultures to study the protective effects of minocycline
- determine the concentration of sphingomyelin from serum samples
- enhance sphingomyelinase activity to study PARK9-mediated exosome biogenesis
General Description
Sphingomyelinase from Bacillus cereus (Bc-Smase) is a Mg2+-containing metalloenzyme. Bacillus cereus sphingomyelinase induces hemolysis of sheep erythrocytes.
Biochem/physiol Actions
Initiates the formation of sphingomyelin-based second messengers. Activates MAPK (mitogen-activated protein kinase) and SAPKs (stress-activated protein kinases); generates ceramide from sphingomyelin.
Properties of SPHINGOMYELINASE
| storage temp. | 2-8°C |
| form | lyophilized powder |
| color | White to off-white |
Safety information for SPHINGOMYELINASE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. |
Computed Descriptors for SPHINGOMYELINASE
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