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HomeProduct name listSPHINGOMYELINASE

SPHINGOMYELINASE

Synonym(s):Sphingomyelin choline phosphohydrolase;Sphingomyelin phosphodiesterase

  • CAS NO.:9031-54-3
  • Molecular Weight: 0
  • MDL number: MFCD00132362
  • EINECS: 232-869-9
  • Update Date: 2026-01-13 11:20:31

What is SPHINGOMYELINASE?

The Uses of SPHINGOMYELINASE

sphingomyelinase is a fluid that can enhance the skin’s moistureretention properties.

The Uses of SPHINGOMYELINASE

Sphingomyelinase from Bacillus cereus has been used:

  • in the measurement of membrane capacitance in brain slices
  • for testing and confirming its silkworm-killing activity
  • in enzyme activity assay and for elucidating its effect on hydrolysis of sphingomyelin in complex lipid mixtures

The Uses of SPHINGOMYELINASE

Sphingomyelinase from Staphylococcus aureus has been used to:

  • induce neurotoxicity in rat cortical cultures to study the protective effects of minocycline
  • determine the concentration of sphingomyelin from serum samples
  • enhance sphingomyelinase activity to study PARK9-mediated exosome biogenesis

General Description

Sphingomyelinase from Bacillus cereus (Bc-Smase) is a Mg2+-containing metalloenzyme. Bacillus cereus sphingomyelinase induces hemolysis of sheep erythrocytes.

Biochem/physiol Actions

Initiates the formation of sphingomyelin-based second messengers. Activates MAPK (mitogen-activated protein kinase) and SAPKs (stress-activated protein kinases); generates ceramide from sphingomyelin.

Properties of SPHINGOMYELINASE

storage temp.  2-8°C
form  lyophilized powder
color  White to off-white

Safety information for SPHINGOMYELINASE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H317:Sensitisation, Skin
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P272:Contaminated work clothing should not be allowed out of the workplace.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

Computed Descriptors for SPHINGOMYELINASE

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