Sodium difluoromethanesulfinate

CAS NO.：275818-95-6
Empirical Formula: CH3F2NaO2S
Molecular Weight: 140.08
MDL number: MFCD24113355
Update Date: 2025-07-16 09:55:30

What is Sodium difluoromethanesulfinate?

The Uses of Sodium difluoromethanesulfinate

Sodium difluoromethanesulfinate as efficient radical fluoroalkylating reagents,it is able to react with conjugated N-arylsulfonated amides to yield the desired fluoroalkylamides.

Reactions

Sodium difluoromethanesulfinate
Ref. 1) He, Z.; Tan, P.; Ni, C.; Hu, J. Org. Lett. 2015, 17, 1838 –1841. (The invention of HCF2SO2Na and H2CFSO2Na as radical fluoroalkylation reagents)
2) Dai, P.; Yu, X.; Teng, P.; Zhang, W.-H.; Deng, C. Org. Lett. 2018, 20, 6901?6905.
3) Zhang, W. et al. Nat. Commun. 2020, 11, art. no. 638. (HCF2SO2Na was referred to as Hu’s reagent)

Safety information for Sodium difluoromethanesulfinate

New Products

4-Fluorobenzaldehyde 3-Bromobenzaldehyde 3-Fluorobenzaldehyde 2-Chlorobenzaldehyde 3-Amino-3-(3-fluorophenyl)propanoic acid 1-Propyl-4-piperidone Nitroso Irbesartan N-Nitroso Nortriptyline 1-nitro-3,5-dimethyl adamantine (NMEM) 3-(2-aminoethyl) benzene sulfonamide Nabumetone Impurity 5 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-one 4-Bromoaniline 2-Chloro-4-Iodopyridine 6CL-HOBT 2-Bromo-4-nitropyridine-N-oxide Methyl 6-Methylnicotinate 5-Chloro-pyridine-2-carboxylic acid amide

Related products of tetrahydrofuran

Sodium trifluoromethanesulfinate