Sodium difluoromethanesulfinate
- CAS NO.：275818-95-6
- Empirical Formula: CH3F2NaO2S
- Molecular Weight: 140.08
- MDL number: MFCD24113355
- Update Date: 2026-05-27 22:38:49
What is Sodium difluoromethanesulfinate?
The Uses of Sodium difluoromethanesulfinate
Sodium difluoromethanesulfinate as efficient radical fluoroalkylating reagents,it is able to react with conjugated N-arylsulfonated amides to yield the desired fluoroalkylamides.
Reactions
Ref. 1) He, Z.; Tan, P.; Ni, C.; Hu, J. Org. Lett. 2015, 17, 1838 –1841. (The invention of HCF2SO2Na and H2CFSO2Na as radical fluoroalkylation reagents)
2) Dai, P.; Yu, X.; Teng, P.; Zhang, W.-H.; Deng, C. Org. Lett. 2018, 20, 6901?6905.
3) Zhang, W. et al. Nat. Commun. 2020, 11, art. no. 638. (HCF2SO2Na was referred to as Hu’s reagent)
Safety information for Sodium difluoromethanesulfinate
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