SNAP
Synonym(s):(±)-S-Nitroso-N-acetylpenicillamine - CAS 79032-48-7 - Calbiochem;SNAP
- CAS NO.：79032-48-7
- Empirical Formula: C7H12N2O4S
- Molecular Weight: 220.25
- MDL number: MFCD00153852
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:22:53
What is SNAP?
Chemical properties
Green Crystalline Solid
The Uses of SNAP
The D-isomer of SNAP. Serves as an NO donor
The Uses of SNAP
The D-isomer of SNAP. Serves as an NO donor.
What are the applications of Application
(±)-S-Nitroso-N-acetylpenicillamine is a cysteine protease inhibitor and spontaneous NO donor in physiological conditions
Definition
ChEBI: A nitroso compound that is N-acetyl-D-penicillamine in which the sulfanyl hydrogen is replaced by a nitroso group.
General Description
Nitric oxide donor that begins to evolve nitric oxide immediately upon solubilization in aqueous buffers (t1/2 = 10 h). Mimics the actions of nitric oxide, including the relaxation of isolated bovine coronary artery rings (EC50 = 130 nM). Markedly activates soluble guanylate cyclase. Also reported to cause the reversible inactivation of protein kinase C activity. Induces apoptosis in mouse thymocytes. Note: 1 set = 4 x 5 mg.
Biological Activity
A stable analog of endogenous S-nitroso compounds. A source of NO in vivo which unlike organic O-nitrates does not induce tolerance. Decomposes slowly in solution with a t ?of 37h.
Biochem/physiol Actions
EC50 = 130 nM in relaxation of isolated bovine coronary artery rings
Storage
Store at -20°C
Properties of SNAP
| Density | 1.36±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | H2O: ≥2 mg/mL |
| form | powder |
| pka | 3.06±0.10(Predicted) |
| color | green |
Safety information for SNAP
Computed Descriptors for SNAP
New Products
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