SNAP

Synonym(s):(±)-S-Nitroso-N-acetylpenicillamine - CAS 79032-48-7 - Calbiochem;SNAP

CAS NO.：79032-48-7
Empirical Formula: C7H12N2O4S
Molecular Weight: 220.25
MDL number: MFCD00153852
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 02:19:01

What is SNAP?

Chemical properties

Green Crystalline Solid

The Uses of SNAP

The D-isomer of SNAP. Serves as an NO donor

The Uses of SNAP

The D-isomer of SNAP. Serves as an NO donor.

What are the applications of Application

(±)-S-Nitroso-N-acetylpenicillamine is a cysteine protease inhibitor and spontaneous NO donor in physiological conditions

Definition

ChEBI: A nitroso compound that is N-acetyl-D-penicillamine in which the sulfanyl hydrogen is replaced by a nitroso group.

General Description

Nitric oxide donor that begins to evolve nitric oxide immediately upon solubilization in aqueous buffers (t_1/2 = 10 h). Mimics the actions of nitric oxide, including the relaxation of isolated bovine coronary artery rings (EC₅₀ = 130 nM). Markedly activates soluble guanylate cyclase. Also reported to cause the reversible inactivation of protein kinase C activity. Induces apoptosis in mouse thymocytes. Note: 1 set = 4 x 5 mg.

Biological Activity

A stable analog of endogenous S-nitroso compounds. A source of NO in vivo which unlike organic O-nitrates does not induce tolerance. Decomposes slowly in solution with a t ?of 37h.