(S)-Oxiranemethanol
Synonym(s):(S)-(−)-2,3-Epoxy-1-propanol;(S)-(−)-Oxirane-2-methanol
- CAS NO.:60456-23-7
- Empirical Formula: C3H6O2
- Molecular Weight: 74.08
- MDL number: MFCD00074874
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 00:04:52
What is (S)-Oxiranemethanol?
Chemical properties
Colorless to light yellow liqui
The Uses of (S)-Oxiranemethanol
Employed in the synthesis of chiral (E)-allylic alcohol side-chains for introduction into prostacyclin and prostaglandin frameworks by cross-metathesis.
What are the applications of Application
(S)-(?)-Glycidol is a chemical employed in the synthesis of chiral (E)-allylic alcohol side-chains
Definition
ChEBI: (S)-glycidol is a glycidol. It is functionally related to a (S)-1,2-epoxypropane. It is an enantiomer of a (R)-glycidol.
General Description
Glycidol or 2,3-epoxy-1-propanol is a highly reactive epoxy derivative, which is generally used as a monomer in the preparation of many polymers like polyesters,?polycarbonates,?polyurethanes,?and polyamides. It is also used in the preparation of detergents, rubbers, perfumes, fabric dyes, varnishes, cosmetics, and paints.
Purification Methods
[S(-)-isomer, § also available on polymer support, has b 49-50o/7mm, 66-67o/19mm, [ ] D -1 5o(neat)], [R(+)-isomer has b 56 -5 6 . 5o/11mm, d 4 1.117, n D 1.429, [ ] D +15o (neat)]. Purify glycidol by fractional distillation.
Properties of (S)-Oxiranemethanol
| Melting point: | 72-73 °C |
| alpha | -15 º (neat) |
| Boiling point: | 66-67 °C19 mm Hg(lit.) |
| Density | 1.116 g/mL at 20 °C(lit.) |
| refractive index | n |
| Flash point: | 178 °F |
| storage temp. | -20°C |
| solubility | Soluble in chloroform, DMSO and methanol. |
| form | Liquid |
| pka | 14.62±0.10(Predicted) |
| color | Pale yellow |
| optical activity | [α]20/D 15°, neat |
| BRN | 79783 |
| CAS DataBase Reference | 60456-23-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Oxiranemethanol, (S)-(60456-23-7) |
Safety information for (S)-Oxiranemethanol
| Signal word | Danger |
| Pictogram(s) |
![]() Skull and Crossbones Acute Toxicity GHS06 ![]() Health Hazard GHS08 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H330:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H341:Germ cell mutagenicity H350:Carcinogenicity |
| Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (S)-Oxiranemethanol
| InChIKey | CTKINSOISVBQLD-VKHMYHEASA-N |
New Products
2-Amino-5-bromo-4-(trifluoromethyl)pyridine Sulfapyridine Fmoc-OSu (R)-(-)-2-Amino-1-propanol Cyclobutanone 5-bromo-4-fluoro-2-nitrobenzaldehyde β-Bromostyrene Ethyl 3-phenylpropanoate Phenethyl cinnamate Dipropyl disulfide N-Vinylformamide 4 pentyn 1 ol Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran








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