S-(-)-LISURIDE
- CAS NO.：18016-80-3
- Empirical Formula: C20H26N4O
- Molecular Weight: 338.45
- MDL number: MFCD00274053
- EINECS: 241-925-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-17 18:22:24
What is S-(-)-LISURIDE?
The Uses of S-(-)-LISURIDE
A dopamine and serotonin receptor partial agonist with high affinity for the dopamine D2, D3 and D4 receptors, as well as serotonin 5-HT1A and 5-HT2A/C receptors. An anti-parkinson agent.
The Uses of S-(-)-LISURIDE
A dopamine and serotonin receptor partial agonist with high affinity for the dopamine D2, D3 and D4 receptors, as well as serotonin 5-HT1A and 5-HT2A/C receptors. An anti-parkinson agent (1,2).
Background
An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists).
Indications
For the management of Parkinson's Disease
Definition
ChEBI: Lisuride is a monocarboxylic acid amide. It has a role as an antiparkinson drug, a serotonergic agonist, a dopamine agonist and an antidyskinesia agent. It derives from a hydride of an ergoline.
Pharmacokinetics
There is evidence that lisuride lowers prolactin levels and, in low doses, prevents migraine attacks.
Metabolism
Not Available
Properties of S-(-)-LISURIDE
| Melting point: | 186° |
| Boiling point: | 603.4±55.0 °C(Predicted) |
| alpha | D20 +313° (c = 0.60 in pyridine) |
| Density | 1.23±0.1 g/cm3(Predicted) |
| pka | 13.06±0.20(Predicted) |
| CAS DataBase Reference | 18016-80-3 |
Safety information for S-(-)-LISURIDE
Computed Descriptors for S-(-)-LISURIDE
New Products
4-Iodo-3,5-dimethylbenzonitrile 2-fluoro-4-iodoaniline 2-(3-Methyl-1,2,4-oxadiazol-5-yl)acetic acid (as potassium salt) 6,6'-methylenebis(9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-2,3-dihydro-1H-carbazol-4(9H)-one) 3-Bromo-2-fluorobenzoic acid Quinuclidine-4-carbonitrile N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (R)-1-Benzyl-3-pyrrolidinecarbonitrile Bupropian related compound F Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 1,4-bis(methylsulfonyl)butane 4-Cyano-N-Methacryloyl-3-Trifluoromethyl Aniline 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzeneRelated products of tetrahydrofuran
![S(+)-N,N-DIETHYL-N'([8ALPHA]-6-METHYLERGOLIN-8-YL)UREA](https://img.chemicalbook.in/CAS/GIF/37686-84-3.gif)
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