(S)-alpha-Amino-2,3-dihydro-4-methoxy-7-nitro-D-oxo-1H-indole-1-pentanoic acid

The Uses of (S)-alpha-Amino-2,3-dihydro-4-methoxy-7-nitro-D-oxo-1H-indole-1-pentanoic acid

MNI-caged-L-glutamate, is a new caged neuroactive amino acid, that use 4-methoxy-7-nitroindolinyl- (MNI) group to make caged ligands specific for glutamate receptor sub-types. MNI-caged-L-glutamate, rapidly release glutamate when photolysed.

What are the applications of Application

MNI-caged-L-glutamate is rapidly and efficiently releases glutamate when photolysed with 300 - 380 nm light.

Biological Activity

Caged glutamate that rapidly and efficiently releases glutamate when photolysed (300-380 nm excitation). Water-soluble, highly resistant to hydrolysis, stable at neutral pH, and pharmacologically inactive at neuronal glutamate receptors (up to mM concentrations). 2.5-fold more efficient at releasing L-glutamate than NI-caged L-glutamate.

Storage

-20°C (protect from light)