(S)-(-)-4-Amino-2-hydroxybutyric acid
- CAS NO.：40371-51-5
- Empirical Formula: C4H9NO3
- Molecular Weight: 119.12
- MDL number: MFCD00674110
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:12:53
What is (S)-(-)-4-Amino-2-hydroxybutyric acid?
Chemical properties
white to light yellow crystal powder
The Uses of (S)-(-)-4-Amino-2-hydroxybutyric acid
(S)-(-)-4-Amino-2-hydroxybutyric Acid is an analogue of γ-aminobutyric acid (GABA) with potential inhibitory activity on GABA binding and uptake by brain. Injection of (S)-(-)-4-Amino-2-hydroxybutyric Acid showed no significant changes in plasma growth hormone (GH) in healthy patients but increased plasma GH, prolactin, and cortisol levels in cerebrovascular patients.
The Uses of (S)-(-)-4-Amino-2-hydroxybutyric acid
(S)-(-)-4-Amino-2-hydroxybutyric acid may be used in the preparation of 6′-amino-1-N-[(S)-4-amino-2-hydroxybutyryl]-6′-deoxylividomycin A.
What are the applications of Application
(S)-(?)-4-Amino-2-hydroxybutyric acid is a building block for enantiopure 3-hydroxypyrrolidin-2-ones
General Description
(S)-(-)-4-Amino-2-hydroxybutyric acid is an important moiety of butirosin, an aminoglycoside antibiotic.
Properties of (S)-(-)-4-Amino-2-hydroxybutyric acid
| Melting point: | 200-203 °C (lit.) |
| Boiling point: | 222.38°C (rough estimate) |
| alpha | -30 º (c=1, water) |
| Density | 1.3126 (rough estimate) |
| refractive index | -30 ° (C=1, H2O) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Methanol (Very Slightly, Heated), Water |
| form | Crystalline Powder, Crystals and/or Chunks |
| pka | 3.47±0.10(Predicted) |
| color | White to beige |
| optical activity | [α]23/D 30°, c = 1 in H2O |
| Water Solubility | almost transparency |
| Sensitive | Hygroscopic |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 40371-51-5(CAS DataBase Reference) |
Safety information for (S)-(-)-4-Amino-2-hydroxybutyric acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for (S)-(-)-4-Amino-2-hydroxybutyric acid
| InChIKey | IVUOMFWNDGNLBJ-VKHMYHEASA-N |
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