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HomeProduct name listRYNTR

RYNTR

Synonym(s):NADPH:Oxidised Thioredoxin Oxidoreductase;ryNTR;Thioredoxin: NADP+ Oxidoreductase

  • CAS NO.:9074-14-0
  • Molecular Weight: 0
  • MDL number: MFCD00678149
  • Update Date: 2026-04-24 14:58:19

What is RYNTR?

The Uses of RYNTR

Thioredoxin Reductase from rat liver can be used for studying the uptake and reduction of a-lipoic acid by utilizing reducing capacity of human erythrocytes. The product can also be used for studying the activation mechanism of transglutaminase 2 (TG2) in the extracellular matrix by using Thioredoxin.

Biochem/physiol Actions

Thioredoxin reductase (TrxR) is a NADPH-dependent oxidoreductase containing one FAD per subunit that reduces the active site disulfide in oxidized thioredoxin (Trx). The molecular weight of the isozymes from mammalian sources vary between 55-67 kDa as compared with 35 kDa in prokaryotes, plants or yeast. The substrate specificity of the mammalian enzyme is much broader than the prokaryotic enzyme reducing both mammalian and E. coli thioredoxins as well as non-disulfide substrates such selenite, lipoic acids, lipid hydroperoxides, and hydrogen peroxide.

Properties of RYNTR

storage temp.  2-8°C
form  buffered aqueous glycerol solution

Safety information for RYNTR

Computed Descriptors for RYNTR

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