RUFLOXACIN
- CAS NO.：101363-10-4
- Empirical Formula: C17H18FN3O3S
- Molecular Weight: 363.41
- MDL number: MFCD00865073
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 23:18:00
What is RUFLOXACIN?
Definition
ChEBI: Rufloxacin is a member of quinolines, a quinolone antibiotic and a fluoroquinolone antibiotic.
Pharmaceutical Applications
A tricyclic fluoroquinolone formulated as the hydrochloride salt. It is inactive against Gram-positive cocci with MICs >2 mg/L. It displays weak activity in vitro against Enterobacteriaceae with the MIC for most species >1 mg/L. Activity against Ps. aeruginosa is poor (MIC 16–32 mg/L). After loading doses of 400 and 600 mg followed with 9 days of either 200 or 300 mg, mean peak plasma levels were around 4.5–7 mg/L, respectively. The mean apparent elimination halflife was 44 h. Approximately 50% is eliminated in the urine.
It has been used in urinary tract infection and chronic prostatitis, but clinical experience is limited.
Properties of RUFLOXACIN
| Boiling point: | 574.6±50.0 °C(Predicted) |
| Density | 1.54 |
| storage temp. | 2-8°C |
| pka | 5.21±0.20(Predicted) |
| CAS DataBase Reference | 101363-10-4 |
Safety information for RUFLOXACIN
Computed Descriptors for RUFLOXACIN
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