RN486
- CAS NO.：1242156-23-5
- Empirical Formula: C35H35FN6O3
- Molecular Weight: 606.69
- MDL number: MFCD24682729
- EINECS: 200-110-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-17 18:22:24
What is RN486?
The Uses of RN486
RN 486 is a Bruton’s tyrosine kinase (Btk) inhibitor, blocking receptor cross-linking-induced degranulation in mast cells. May be used in the prevention of arthritis and other autoimmune diseases.
Properties of RN486
| Boiling point: | 868.6±65.0 °C(Predicted) |
| Density | 1.378±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | ≥30.35 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH |
| form | solid |
| pka | 13.95±0.10(Predicted) |
| color | Off-white to light yellow |
| CAS DataBase Reference | 1242156-23-5 |
Safety information for RN486
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for RN486
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