(R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
Synonym(s):(R)-4,5-Dihydro-3-hydroxy-2(3H)-furanone
- CAS NO.：56881-90-4
- Empirical Formula: C4H6O3
- Molecular Weight: 102.09
- MDL number: MFCD00211246
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is (R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE?
The Uses of (R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
(R)-(+)-α-Hydroxy-γ-butyrolactone can be used as a starting material to synthesize:
- δ-Azaproline by reacting with benzyloxycarbonyl aminophthalimide via Mitsunobu reactions.
- Homochiral (R)-2,4-dihydroxybutyramide seco-pseudonucleoside reagents.
- Botryolide B via esterification and ring-closing metathesis reaction.
- Pregnane derivatives containing γ-butyrolactones as potential glucocorticoid agonists.
Properties of (R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
| Boiling point: | 133 °C/10 mmHg (lit.) |
| alpha | +66°(23℃, c=1.15, CHCl3) |
| Density | 1.309 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | 2-8°C |
| form | clear liquid |
| pka | 13.07±0.20(Predicted) |
| Specific Gravity | 1.32 |
| color | Colorless to Light yellow |
| optical activity | [α]23/D +66°, c = 1.15 in chloroform |
| BRN | 80588 |
| CAS DataBase Reference | 56881-90-4(CAS DataBase Reference) |
Safety information for (R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for (R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
New Products
Indole Methyl Resin tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Boc-His(Boc)-OH 2-CTC Resin 4-Chloro-7-tosy1-7Hpyrrolo[2,3-d]pyrimidine 5,7-Dibromo-1H-indole 2,5-dichloro-N-hydroxy-4,6-dimethylpyridine-3-carboximidamide 2,2-Dimethoxy-7-azaspiro[3.5]nonane hydrochloride 4-chloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl) R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDIIMIDAZOLE 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID 4-((2-hydroxyethyl)thio)benzoic acid 1-(TERT-BUTOXYCARBONYL)-2-PYRROLIDINONE Methyl 6-methylnicotinate 3-Pyridineacrylic acid tert-Butyl carbazate TETRAHYDRO-2H-PYRAN-3-OL 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile 2,4-dihydroxybenzaldehyde 1,3-Diethyl-1,3-Diphenylurea Methyl 2-methylquinoline-6-carboxylateRelated products of tetrahydrofuran
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