D-ERYTHRONOLACTONE
Synonym(s):(3R-cis) (−)-Dihydro-3,4-dihydroxy-2(3H)-furanone;D -Erythronic acid γ-lactone;D -Erythronolactone
- CAS NO.：15667-21-7
- Empirical Formula: C4H6O4
- Molecular Weight: 118.09
- MDL number: MFCD00077763
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:21
What is D-ERYTHRONOLACTONE?
Chemical properties
D-ERYTHRONOLACTONE is white to light yellow crystal powde
The Uses of D-ERYTHRONOLACTONE
D-ERYTHRONOLACTONE is a chiral synthon used for the synthesis of certain natural products such as the leukotrienes
The Uses of D-ERYTHRONOLACTONE
D-erythrono-1,4-lactone is a potential substrates of dihydroxy acid dehydratase.
The Uses of D-ERYTHRONOLACTONE
A chiral synthon used for the synthesis of certain natural products such as the leukotrienes.
What are the applications of Application
D-Erythronolactone is a chiral synthon used to create analogs of certain natural products
Definition
ChEBI: Erythrono-1,4-lactone is a butan-4-olide that is dihydrofuran-2-one substituted at C-3 and C-4 by hydroxy groups (the 3R,4R-diastereomer). It is a butan-4-olide and a diol.
Purification Methods
Recrystallise it from EtOAc (20 parts) or isoPrOH (3 parts). [Baker & MacDonald J Am Chem Soc 82 230 1960, Glattfeld & Forbrich J Am Chem Soc 56 1209 1934, Weidenhagen & Wegner Chem Ber 72 2010 1939, Musich & Rapoport J Am Chem Soc 100 4865 1978, Beilstein 18/2 V 457.]
Properties of D-ERYTHRONOLACTONE
| Melting point: | 100-102 °C(lit.) |
| Boiling point: | 140.59°C (rough estimate) |
| Density | 1.0887 (rough estimate) |
| refractive index | -71 ° (C=1, H2O) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 12.34±0.40(Predicted) |
| color | White to Off-White |
| optical activity | [α]20/D 71°, c = 1 in H2O |
| BRN | 81073 |
| CAS DataBase Reference | 15667-21-7(CAS DataBase Reference) |
Safety information for D-ERYTHRONOLACTONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for D-ERYTHRONOLACTONE
New Products
2-Ethoxyphenol Methyl 2-methoxy-5-sulfamoylbenzoate 3,6-Dichloropyridazine Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 3,6-Dichloro-4-Isopropylpyridazine 2-[(2-Ethoxyphenoxy)methyl]oxirane 4-Morpholinoaniline 2-Chloromethyl-6-methyl-pyridine 1-Indanone tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate 2-Pyridinecarboxaldehdye 6-Methyl-2-pyridinemethanol 4-Bromo-2-fluoro-N-methylbenzamide 3-Azetidinecarboxylic acid N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-6-methoxypyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide (R)-4-Boc-morpholine-3-carboxylic acid (Required high chiral purity NLT:99.5%) Tetrahydro-3-(2-methyl-2- nitropropyl)-2H-pyran-2-one 3-Bromo-2-fluorobenzonitrile Desoximetasone Boron Triiodide Nicotinic acid RAPAMYCIN Pentachlorobenzonitrile BudesonideRelated products of tetrahydrofuran
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