D-ERYTHRONOLACTONE
Synonym(s):(3R-cis) (−)-Dihydro-3,4-dihydroxy-2(3H)-furanone;D -Erythronic acid γ-lactone;D -Erythronolactone
- CAS NO.：15667-21-7
- Empirical Formula: C4H6O4
- Molecular Weight: 118.09
- MDL number: MFCD00077763
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:17:25
What is D-ERYTHRONOLACTONE?
Chemical properties
D-ERYTHRONOLACTONE is white to light yellow crystal powde
The Uses of D-ERYTHRONOLACTONE
D-ERYTHRONOLACTONE is a chiral synthon used for the synthesis of certain natural products such as the leukotrienes
The Uses of D-ERYTHRONOLACTONE
D-erythrono-1,4-lactone is a potential substrates of dihydroxy acid dehydratase.
The Uses of D-ERYTHRONOLACTONE
A chiral synthon used for the synthesis of certain natural products such as the leukotrienes.
What are the applications of Application
D-Erythronolactone is a chiral synthon used to create analogs of certain natural products
Definition
ChEBI: Erythrono-1,4-lactone is a butan-4-olide that is dihydrofuran-2-one substituted at C-3 and C-4 by hydroxy groups (the 3R,4R-diastereomer). It is a butan-4-olide and a diol.
Purification Methods
Recrystallise it from EtOAc (20 parts) or isoPrOH (3 parts). [Baker & MacDonald J Am Chem Soc 82 230 1960, Glattfeld & Forbrich J Am Chem Soc 56 1209 1934, Weidenhagen & Wegner Chem Ber 72 2010 1939, Musich & Rapoport J Am Chem Soc 100 4865 1978, Beilstein 18/2 V 457.]
Properties of D-ERYTHRONOLACTONE
| Melting point: | 100-102 °C(lit.) |
| Boiling point: | 140.59°C (rough estimate) |
| Density | 1.0887 (rough estimate) |
| refractive index | -71 ° (C=1, H2O) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 12.34±0.40(Predicted) |
| color | White to Off-White |
| optical activity | [α]20/D 71°, c = 1 in H2O |
| BRN | 81073 |
| CAS DataBase Reference | 15667-21-7(CAS DataBase Reference) |
Safety information for D-ERYTHRONOLACTONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for D-ERYTHRONOLACTONE
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 1-AMino-cyclobutaneMethanol HCl TETRABUTYLAMMONIUM CYANIDE 3-Amino-3-(3-fluorophenyl)propanoic acid 3-Amino-3-(4-methylphenyl)propionic acid 3-AMINO-3-(3-CHLORO-PHENYL)-PROPIONIC ACID Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 4 - fluoro- 2 - methoxy- 5 - nitroaniline 1-(2-amino-5-hydroxy phenyl)propan-1-one tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-amino-5-nitrobenzonitrile (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanideRelated products of tetrahydrofuran
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