(R)-(-)-3-Hydroxytetrahydrofuran
Synonym(s):(R)-(-)-Tetrahydro-3-furanol
- CAS NO.：86087-24-3
- Empirical Formula: C4H8O2
- Molecular Weight: 88.11
- MDL number: MFCD00067101
- EINECS: 617-796-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-25 17:15:13
What is (R)-(-)-3-Hydroxytetrahydrofuran?
Chemical properties
Colorless to light yellow liqui
The Uses of (R)-(-)-3-Hydroxytetrahydrofuran
(R)-(-)-3-Hydroxytetrahydrofuran is used as a chemical reactant in the synthesis of pharmaceutical agents. Empagliflozin is synthesized using this reactant
The Uses of (R)-(-)-3-Hydroxytetrahydrofuran
(R)-(-)-3-Hydroxytetrahydrofuran may be used as building block in the synthesis of potent HIV protease inhibitors.
Properties of (R)-(-)-3-Hydroxytetrahydrofuran
| Boiling point: | 181 °C (lit.) |
| alpha | -18.5 º (c=2 MeOH) |
| Density | 1.097 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 180 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform, Methanol (Slightly) |
| form | Liquid |
| pka | 14.49±0.20(Predicted) |
| Specific Gravity | 1.097 |
| color | Clear colorless |
| optical activity | [α]20/D 18°, c = 2.4 in methanol |
| InChI | InChI=1S/C4H8O2/c5-4-1-2-6-3-4/h4-5H,1-3H2/t4-/m1/s1 |
| CAS DataBase Reference | 86087-24-3(CAS DataBase Reference) |
Safety information for (R)-(-)-3-Hydroxytetrahydrofuran
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (R)-(-)-3-Hydroxytetrahydrofuran
| InChIKey | XDPCNPCKDGQBAN-SCSAIBSYSA-N |
| SMILES | O1CC[C@@H](O)C1 |
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