(R)-(-)-5-OXOTETRAHYDROFURAN-2-CARBOXYLIC ACID
Synonym(s):(R)-γ-Carboxy-γ-butyrolactone;(R)-5-Oxotetrahydro-2-furancarboxylic acid
- CAS NO.：53558-93-3
- Empirical Formula: C5H6O4
- Molecular Weight: 130.1
- MDL number: MFCD00011567
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:25:02
What is (R)-(-)-5-OXOTETRAHYDROFURAN-2-CARBOXYLIC ACID?
Chemical properties
white crystalline powder
The Uses of (R)-(-)-5-OXOTETRAHYDROFURAN-2-CARBOXYLIC ACID
(R)-5-Oxotetrahydrofuran-2-carboxylic Acid is an intermediate used to synthesize 2'',3''-dideoxy-4''-selenonucleosides as potential antiviral agents.
General Description
(R)-(?)-5-Oxo-2-tetrahydrofurancarboxylic acid belongs to the class of furans, considered as heterocyclic building blocks. It is used as an HPLC derivatization reagent for UV/Vis detection.
Properties of (R)-(-)-5-OXOTETRAHYDROFURAN-2-CARBOXYLIC ACID
| Melting point: | 71-73 °C (lit.) |
| Boiling point: | 165-167 °C/0.3 mmHg (lit.) |
| alpha | -14°(D/20℃) (c=5, メタノール) |
| Density | 1.3985 (rough estimate) |
| refractive index | 1.5800 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 3.11±0.20(Predicted) |
| optical activity | [α]20/D 14°, c = 5 in methanol |
| BRN | 1424499 |
| CAS DataBase Reference | 53558-93-3(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Furancarboxylic acid, tetrahydro-5-oxo-, (2R)- (53558-93-3) |
Safety information for (R)-(-)-5-OXOTETRAHYDROFURAN-2-CARBOXYLIC ACID
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (R)-(-)-5-OXOTETRAHYDROFURAN-2-CARBOXYLIC ACID
| InChIKey | QVADRSWDTZDDGR-GSVOUGTGSA-N |
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![2-[[(4S)-4-[[(2,6-Difluorophenyl)acetyl]amino]-3-oxotetrahydroisoxazol]-2-yl]-5-oxotetrahydrofuran-2-carboxylic acid sodium salt](https://img.chemicalbook.in/)
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