(R)-5-Hydroxymethyldihydrofuran-2-one
Synonym(s):(R)-γ-Hydroxymethyl-γ-butyrolactone;(R)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone;(R)-5-Hydroxymethyl-2-oxotetrahydrofuran
- CAS NO.：52813-63-5
- Empirical Formula: C5H8O3
- Molecular Weight: 116.12
- MDL number: MFCD00040528
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 17:33:19
What is (R)-5-Hydroxymethyldihydrofuran-2-one?
The Uses of (R)-5-Hydroxymethyldihydrofuran-2-one
Versatile chiral synthon used in the synthesis of natural and unnatural products.
What are the applications of Application
(R)-(?)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone is a versatile chiral synthon used in the synthesis of natural and unnatural products
Purification Methods
Purify it by column chromatography on Silica gel 60 (Merck 70-230 mesh) and eluting with 7% EtOH/73% CHCl3. IR
Properties of (R)-5-Hydroxymethyldihydrofuran-2-one
| Boiling point: | 101-102 °C0.048 mm Hg(lit.) |
| alpha | -56 º (c=3 in chloroform) |
| Density | 1.238 g/mL at 20 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | 2-8°C |
| pka | 14.12±0.10(Predicted) |
| optical activity | [α]20/D 56°, c = 3 in chloroform |
| BRN | 1680285 |
Safety information for (R)-5-Hydroxymethyldihydrofuran-2-one
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. |
Computed Descriptors for (R)-5-Hydroxymethyldihydrofuran-2-one
New Products
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