2,3-Dihydrofuran
Synonym(s):2,3-DHF
- CAS NO.：1191-99-7
- Empirical Formula: C4H6O
- Molecular Weight: 70.09
- MDL number: MFCD00003205
- EINECS: 214-747-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-04 15:31:03
What is 2,3-Dihydrofuran?
Chemical properties
clear colourless liquid
The Uses of 2,3-Dihydrofuran
2,3-Dihydrofuran is a dehydration product of tetrahydrofuran (THF). 2,3-Dihydrofuran is also used in the preparation of niologically active compounds such as antitumor agents.
The Uses of 2,3-Dihydrofuran
2,3-Dihydrofuran is a versatile reagent used in lanthanide-catalyzed Diels-Alder reactions with 2-pyrones and in Rh(II)-stabilized cycloadditions with vinylcarbenoids. It is applied for alkylation by active methylene compounds, catalyzed by trans-Dichlorobis(triphenyl-phosphine)-palladium(II). It is also used in the preparation of biologically active compounds such as antitumor agents.
What are the applications of Application
2,3-Dihydrofuran is a versatile synthesis reagent
Definition
ChEBI: 2,3-dihydrofuran is a dihydrofuran.
General Description
The enantioselective Heck arylation of 2,3-dihydrofuran with aryl iodides was studied.
Properties of 2,3-Dihydrofuran
| Melting point: | 280 °C(Solv: trichloroethylene (79-01-6); ethanol (64-17-5)) |
| Boiling point: | 54-55 °C (lit.) |
| Density | 0.927 g/mL at 25 °C (lit.) |
| vapor pressure | 14.46 psi ( 55 °C) |
| refractive index | n |
| Flash point: | −12 °F |
| storage temp. | 2-8°C |
| solubility | soluble in Chloroform |
| form | Liquid |
| color | Clear colorless |
| Water Solubility | slightlu soluble |
| BRN | 103168 |
| CAS DataBase Reference | 1191-99-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Furan, 2,3-dihydro-(1191-99-7) |
| EPA Substance Registry System | Furan, 2,3-dihydro- (1191-99-7) |
Safety information for 2,3-Dihydrofuran
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H225:Flammable liquids H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P242:Use only non-sparking tools. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,3-Dihydrofuran
| InChIKey | JKTCBAGSMQIFNL-UHFFFAOYSA-N |
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