Medetomidine hydrochloride

Description

Medetomidine hydrochloride is a potent, highly selective α2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for α2- and α1-adrenoceptors respectively). It is an imidazole compound. Medetomidine hydrochloride shows greater selectivity over α1-adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). In addition, it influences the adrenergic system by mimicking the action of adrenergic neurotransmitters.

Chemical properties

White Solid

The Uses of Medetomidine hydrochloride

α2-Adrenergic agonist. Sedative; analgesic.

The Uses of Medetomidine hydrochloride

Medetomidine is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor

The Uses of Medetomidine hydrochloride

An α2-Adrenergic agonist. Sedative; analgesic.

What are the applications of Application

Medetomidine hydrochloride is a potent and highly selective α2-adrenoceptor agonist used as an anesthetic and analgesic.

Definition

ChEBI: Medetomidine hydrochloride is a hydrochloride.

Biological Activity

medetomidine is a selective α2-adrenoceptor agonist, with ki of 1.08 nm, exhibts 1620-fold selectivity over α1-adrenoceptor.

Side Effects

Medetomidine hydrochloride is an alpha-2 adrenoreceptor agonist. Symptoms after absorption may involve clinical effects, including dose dependent sedation, respiratory depression, bradycardia, hypotension, a dry mouth, and hyperglycaemia. Ventricular arrhythmias have also been reported. Respiratory and haemodynamic symptoms should be treated symptomatically.

Storage

Desiccate at RT