(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
Synonym(s):L -α,β-Isopropylideneglycerol;L -2,3-O-isopropylidene-sn-glycerol;2,3-Isopropylidene-sn-glycerol
- CAS NO.：14347-78-5
- Empirical Formula: C6H12O3
- Molecular Weight: 132.16
- MDL number: MFCD00003213
- EINECS: 604-360-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-03 09:51:45
What is (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol?
Chemical properties
colourless liquid
The Uses of (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
A MEK inhibitor
The Uses of (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol may be used to prepare:
- (R)-2,2-Dimethyl-4-benzoxymethyl-1,3-dioxolane.
- ((S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate)-1,3-dioxolane.
- (S)-Glyceraldehyde acetonide.
- Tetraoxaspiroundecanes, diglycerides, glyceryl phosphates, and spiropyrans.
Properties of (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
| Boiling point: | 72-73 °C/8 mmHg (lit.) |
| alpha | -13.7 º (neat) |
| Density | 1.062 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 176 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Liquid |
| pka | 14.20±0.10(Predicted) |
| Specific Gravity | 1.062 |
| color | Clear colorless to light yellow |
| optical activity | [α]20/D 13.7°, neat |
| Water Solubility | miscible |
| Merck | 14,5213 |
| BRN | 80117 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 14347-78-5(CAS DataBase Reference) |
| NIST Chemistry Reference | D-Acetone glycerol(14347-78-5) |
Safety information for (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H227:Flammable liquids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use … for extinction. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..… |
Computed Descriptors for (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
| InChIKey | RNVYQYLELCKWAN-RXMQYKEDSA-N |
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