(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER
Synonym(s):α,β-Isopropylidene-D -glyceric acid methyl ester;Methyl α,β-isopropylidene-D -glycerate;Methyl 2,3-O-isopropylidene-D -glycerate
- CAS NO.：52373-72-5
- Empirical Formula: C7H12O4
- Molecular Weight: 160.17
- MDL number: MFCD00066527
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:23:56
What is (R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER?
Chemical properties
Colorless to light yellowliqui
The Uses of (R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Methyl Ester is a dioxolane derivative used in the preparation of matrix metalloproteinases (MMP) inhibitors.
The Uses of (R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER
Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate may be used as a starting material to synthesize (2R)-[1-2H2]-glycerol, a probe to study the stereochemistry of glycerol metabolism in Streptomyces cattleya. It may also be used to synthesize organic building blocks like (R)-2,3-dihydroxy-3-methylbutyl toluene-p-sulfonate and (2S,8R)-2-amino-8-[(R) 2,2-dimethyl-1,3-dioxolan-4-yl]-8-oxooctanoic acid.
Properties of (R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER
| Boiling point: | 70-75 °C/10 mmHg (lit.) |
| Density | 1.106 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 173 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly) |
| form | Oil |
| color | Yellow |
| optical activity | [α]20/D +8.5°, c = 1.5 in acetone |
| BRN | 4292353 |
| CAS DataBase Reference | 52373-72-5(CAS DataBase Reference) |
Safety information for (R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H227:Flammable liquids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..… |
Computed Descriptors for (R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER
| InChIKey | DOWWCCDWPKGNGX-RXMQYKEDSA-N |
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