(R)-(-)-2-Amino-3-methyl-1-butanol
Synonym(s):D -Valinol
- CAS NO.：4276-09-9
- Empirical Formula: C5H13NO
- Molecular Weight: 103.16
- MDL number: MFCD00064297
- EINECS: 217-975-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:15:12
What is (R)-(-)-2-Amino-3-methyl-1-butanol?
Chemical properties
white to light yellow crystal powde
The Uses of (R)-(-)-2-Amino-3-methyl-1-butanol
D-Valinol is used as a reagent in the synthesis of the HIV type 1 integrase inhibitor Elvitegravir (E509000). D-Valinol is also used in the preparation of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally active GSK-3β inhibitors for Alzheimer''s disease.
Properties of (R)-(-)-2-Amino-3-methyl-1-butanol
| Melting point: | 35-36 °C(lit.) |
| alpha | -16.5 º (c=10, EtOH) |
| Boiling point: | 189-190 °C(lit.) |
| Density | 0.931 g/mL at 20 °C(lit.) |
| refractive index | n |
| Flash point: | 194 °F |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 12.82±0.10(Predicted) |
| form | Low Melting Crystals or Crystalline Mass |
| color | White to light yellow |
| optical activity | [α]20/D 16°, c = 10 in ethanol |
| Sensitive | Air Sensitive |
| BRN | 1719138 |
| CAS DataBase Reference | 4276-09-9(CAS DataBase Reference) |
Safety information for (R)-(-)-2-Amino-3-methyl-1-butanol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see … on this label). P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for (R)-(-)-2-Amino-3-methyl-1-butanol
| InChIKey | NWYYWIJOWOLJNR-YFKPBYRVSA-N |
(R)-(-)-2-Amino-3-methyl-1-butanol manufacturer
New Products
DL-beta-(3-Bromophenyl)alanine Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) N,N CARBONYL DIIMIDAZOLE Levothyroxine Impurity-F Montelukast EP Impurity-D/Montelukast USP Related Compound C Atorvastatin FXA Impurity/Atorvastatin Cyclic 6-Hydroxy Impurity Sodium Salt Isosulfan blue Keto N-Oxide Impurity Ivermectin Impurity F N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene CSA (DL-10-Camphorsulfonic Acid) 2-Hydroxy-4-methylnicotinic acid 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioateRelated products of tetrahydrofuran
You may like
-
4276-09-9 98%View Details
4276-09-9 -
D-Valinol, 97% 99%View Details
4276-09-9 -
D-(-)-Valinol CAS 4276-09-9View Details
4276-09-9 -
D-Valinol CAS 4276-09-9View Details
4276-09-9 -
D-Valinol 98% CAS 4276-09-9View Details
4276-09-9 -
D-Valinol, 98% CAS 4276-09-9View Details
4276-09-9 -
(R)-(−)-2-Amino-3-methyl-1-butanol CAS 4276-09-9View Details
4276-09-9 -
1428243-26-8 98+View Details
1428243-26-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.