D-(-)-Asparagine monohydrate
Synonym(s):(R)-(-)-2-Aminosuccinamic acid;(R)-2-Aminosuccinic acid 4-amide;(D )-Aspartic acid 4-amide
- CAS NO.：2058-58-4
- Empirical Formula: C4H8N2O3
- Molecular Weight: 132.12
- MDL number: MFCD00149558
- EINECS: 218-163-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:20:43
What is D-(-)-Asparagine monohydrate?
Chemical properties
crystalline powder
The Uses of D-(-)-Asparagine monohydrate
D-Asparagine is an isomer of L-Asparagine (A790005) and is used by bacteria (such as Saccharomyces cerevisiae) as a sole nitrogen source for replication. L-Asparagine is also a competitive inhibitor of staphylococcal L-asparaginase and is used as a reagent to synthesize peptide antibiotics.
Definition
ChEBI: An optically active form of asparagine having D-configuration.
Synthesis Reference(s)
Chemical and Pharmaceutical Bulletin, 35, p. 2994, 1987 DOI: 10.1248/cpb.35.2994
Properties of D-(-)-Asparagine monohydrate
| Melting point: | 280 °C (dec.) (lit.) |
| Boiling point: | 438.0±40.0 °C(Predicted) |
| alpha | -35 º (c=5, 5M HCl) |
| Density | 1.404±0.06 g/cm3(Predicted) |
| storage temp. | Store at 0-5°C |
| solubility | Aqueous Acid (Sparingly), Water (Slightly, Sonicated) |
| form | Solid |
| pka | 2.17(at 20℃) |
| color | White to Off-White |
| optical activity | [α]20/D 35°, c = 5 in 5 M HCl |
| Merck | 13,842 |
| BRN | 1723526 |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 2058-58-4(CAS DataBase Reference) |
Safety information for D-(-)-Asparagine monohydrate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for D-(-)-Asparagine monohydrate
| InChIKey | DCXYFEDJOCDNAF-UWTATZPHSA-N |
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