PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2
Synonym(s):(D-Ala-6) Luteinizing Hormone Releasing Hormone
- CAS NO.：51230-19-4
- Empirical Formula: C56H77N17O13
- Molecular Weight: 1196.32
- MDL number: MFCD00133502
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-21 22:16:43
What is PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2?
The Uses of PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2
[D-Ala6]-LH-RH acetate salt hydrate has been used to induce ovulation and to synchronize the reproductive cycle in Sprague-Dawley female rats.
Biochem/physiol Actions
(D-Ala6)-LH-RH is a GnRH (gonadotropin-releasing hormone) agonist. GnRH, which is also referred to as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.
Properties of PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2
| Density | 1.52±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| pka | 9.82±0.15(Predicted) |
Safety information for PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2
| Signal word | Danger |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H360:Reproductive toxicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2
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![[D-Lys6]-LHRH](https://img.chemicalbook.in/CAS/GIF/130751-49-4.gif)
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