PTIO

Synonym(s):2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide;2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide;PTIO - CAS 18390-00-6 - Calbiochem

CAS NO.：18390-00-6
Empirical Formula: C13H17N2O2
Molecular Weight: 233.29
MDL number: MFCD00059929
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 02:24:41

What is PTIO?

Description

PTIO is an oxidizing reagent that reacts with nitric oxide to form nitric dioxide and corresponding imino nitroxides. It can be used to assay nitric oxide production when examining nitric oxide synthase inhibitory activity.

Chemical properties

blue crystals

The Uses of PTIO

PTIO is a nitric oxide (NO) radical scavenger used to inhibit physiological effects of NO.

The Uses of PTIO

2-phenyl-4, 4, 5, 5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIO) has been used as a nitric oxide (NO) scavenger.

What are the applications of Application

PTIO is a nitric oxide (NO) radical scavenger used to inhibit physiological effects of NO

Synthesis Reference(s)

Journal of the American Chemical Society, 90, p. 1078, 1968 DOI: 10.1021/ja01006a053

General Description

Nitric oxide radical scavenger. Reacts with nitric oxide in a stoichiometric manner without affecting nitric oxide synthase activity. Inhibits the enhanced vascular permeability in solid tumors.