PROCATEROL HYDROCHLORIDE
- CAS NO.：62929-91-3
- Empirical Formula: C16H23ClN2O3
- Molecular Weight: 326.82
- MDL number: MFCD04221378
- EINECS: 263-763-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-20 16:56:14
What is PROCATEROL HYDROCHLORIDE?
Description
Procaterol is an agonist of β2-adrenergic receptors (β2-ARs). It binds to (Kd = 46 pM), and is selective for, β2-ARs over β1-ARs (Kd = 4,000 pM). Procaterol binds more potently to β2-ARs in isolated guinea pig lung than to β1-ARs in isolated guinea pig cardiac ventricle in the presence (IC50s = 175 and 1,660 nM, respectively) and absence of GTP (; IC50s = 55.1 and 1,660 nM, respectively). It inhibits contractions induced by acetylcholine in isolated guinea pig trachea (EC50 = 10.5 nM). In vivo, procaterol inhibits histamine-induced airflow obstruction in a guinea pig model of ovalbumin-sensitized asthma when administered via inhalation at a dose of 10 μg/ml.
The Uses of PROCATEROL HYDROCHLORIDE
Procaterol Hydrochloride is a short-acting pulmonary β2-agonist for asthma treatment.
The Uses of PROCATEROL HYDROCHLORIDE
adrenergic agonists
What are the applications of Application
Procaterol hydrochloride is a very potent and specific β2 agonist
General Description
Procaterol is used to prevent lung fibroblast migration. It has anti-inflammatory properties. It can block type 2 T helper (Th2)-related chemokine production in human monocytes and bronchial epithelial cells.
Biological Activity
Specific and very potent β 2 agonist.
Biochem/physiol Actions
β2-adrenoceptor agonist; bronchodilator.
Storage
Store at RT
Properties of PROCATEROL HYDROCHLORIDE
| storage temp. | 2-8°C |
| solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
| form | Powder |
| Stability: | Hygroscopic |
Safety information for PROCATEROL HYDROCHLORIDE
Computed Descriptors for PROCATEROL HYDROCHLORIDE
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