Poziotinib (HM781-36B)
- CAS NO.：1092364-38-9
- Empirical Formula: C23H21Cl2FN4O3
- Molecular Weight: 491.34
- MDL number: MFCD28044290
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-14 09:55:04
What is Poziotinib (HM781-36B)?
Description
Poziotinib is a TKI that covalently and irreversibly inhibits EGFR and HER2, and is unique because of its small terminal group and flexible quinazoline core. Its small size and flexibility allow it to evade the steric hindrance which affects other EGFR TKIs [138].
The Uses of Poziotinib (HM781-36B)
Poziotinib can be used to inhibit the growth of cancer cells.
Properties of Poziotinib (HM781-36B)
| Melting point: | 187 - 190° C |
| Boiling point: | 629.7±55.0 °C(Predicted) |
| Density | 1.409±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | Chloroform (Slightly), DMSO (Slightly, Sonicated) |
| form | Solid |
| pka | 5.35±0.30(Predicted) |
| color | White to Pale Beige |
| CAS DataBase Reference | 1092364-38-9 |
Safety information for Poziotinib (HM781-36B)
Computed Descriptors for Poziotinib (HM781-36B)
New Products
4-Nitrobenzoic acid p-Tolualdehyde 4-Chlorobenzaldehyde 2-Fluorobenzaldehyde Diethylene glycol monomethyl ether 3-Chlorobenzaldehyde N5-(2-aminoethyl)pyridine-2,5-diamine hydrochloride Ornidazole EP impurity C N-Nitroso Desloratadine Domperidone Impurity Valsartan Desalkyl Clomiphene benzophenone analog 3-(2-Chloroacetyl)pyridine hydrochloride 5,7-Dichloro-3H-Imidazo(4,5b)Pyridine 4-Piperidinecarboxylic Acid Ethyl Ester 2-Chloro-3-Fluoro-4-Iodopyridine 5-Amino-2,4-dichloropyridine 3,5-Dibromo-2-NitropyridineRelated products of tetrahydrofuran
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