Ponesterone A
Synonym(s):2β,3β,14α,20R,22R-Pentahydroxy-5β-cholest-7-en-6-one;25-Deoxy-20-hydroxyecdysone;25-Deoxyecdysterone
- CAS NO.：13408-56-5
- Empirical Formula: C27H44O6
- Molecular Weight: 464.63
- MDL number: MFCD00272144
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is Ponesterone A?
Description
Ponesterone A, a steroidal compound, falls under the category of ecdysone and can be found in various sources throughout nature. It was first isolated from insect plants by Nakanishi and Horm in 1966. Compared to β-ecdysone, Ponesterone proves to be 3-100 times more potent in specific neurosensory systems.
The Uses of Ponesterone A
Ponasterone A is an Ecdysone analog.
The Uses of Ponesterone A
Ponasterone A has been used to induce the expression of human huntingtin (HTT).
What are the applications of Application
Ponasterone A is an insect steroid hormone analog that can regulate the metamorphosis of Drosphila.
Definition
ChEBI: Ponasterone A is a 2beta-hydroxy steroid, a 3beta-hydroxy steroid, a 14alpha-hydroxy steroid, a 20-hydroxy steroid, a 22-hydroxy steroid, a 6-oxo steroid and a phytoecdysteroid.
Biochem/physiol Actions
Ponasterone A is an analogue of ecdysone. It induced death of non-adapted insects may be related to PoA regulating different set of genes when compared to 20E.
Storage
+4°C
Properties of Ponesterone A
| Melting point: | 259-260° (dec) |
| Boiling point: | 640.5±55.0 °C(Predicted) |
| alpha | D15 +90° (methanol) |
| Density | 1.22±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | Methanol (Slightly, Sonicated), Pyridine (Slightly) |
| form | White to off-white powder. |
| pka | 14.13±0.70(Predicted) |
| color | White to Off-White |
| CAS DataBase Reference | 13408-56-5(CAS DataBase Reference) |
Safety information for Ponesterone A
Computed Descriptors for Ponesterone A
| InChIKey | PJYYBCXMCWDUAZ-JJJZTNILSA-N |
New Products
3-AMINO-3-(2-CHLORO-PHENYL)-PROPIONIC ACID 4-Fluorophenylglycine 1-Boc-3-(cyanomethyl)azetidine Dimedone 1-N-Boc-3-(aminoethyl)azetidine N-BOC-piperidine-4-carboxylic acid 4,6-Dichlororesorcinol 5-Amino-2-Bromo-3-Chloropyridine 2-Picolinic acid N-oxide 4-Butyl Resorcinol 2-Bromo-5-Chloropyridine 5-Bromo-2-Hydroxy-3-Nitro Pyridine 2-Amino-4-phenyl-thiazole N-(4-Bromophenyl)-2-chloroacetamide TRIFLOURO ACETICACID-D METHANE SULFONIC ACID-D4 PHOSPORIC ACID-D3 85 W% IN D2O DEUTERIUM OXIDE FOR NMR BENZENE-D6 TOLUENE-D3Related products of tetrahydrofuran
![PONASTERONE A, [24,25,26,27-3H(N)],PONASTERONE A, [24,25,26,27-3H(H)]](https://img.chemicalbook.in/StructureFile/ChemBookStructure3/GIF/CB4263191.gif)
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