Polymethylene polyphenyl polyisocyanate

Synonym(s):PAPI 2027;PMDI;Polymethylene polyphenyl isocyanate

CAS NO.：9016-87-9
Empirical Formula: C8H7NO2
Molecular Weight: 149.14668
MDL number: MFCD00072953
EINECS: 922-627-7
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:23:07

Polymethylene polyphenyl polyisocyanate Structural

What is Polymethylene polyphenyl polyisocyanate?

Description

Polymethylene polyphenyl polyisocyanate is a chain extender and a cross-linker that is used in the formation of a polyurethane system by forming amide linkages (?NCO).

Chemical properties

liquid

The Uses of Polymethylene polyphenyl polyisocyanate

Poly[methylene(polyp?henyl Isocyanate)?] is an engineering polymer used in the synthesis of highly resiliant polyurethane foams with flame retardancy.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.

Definition

A polymer of diphenylmethane-4,4′-diisocyanate.

What are the applications of Application

Polymethylene polyphenyl polyisocyanate can be used as a cross-linker to DNA and CTMA based films for the fabrication of biomaterials for organic electronic devices. It can be used in the formation of polyurethane based materials for non-linear optical applications.

General Description

Dark-brown liquid with a weak odor. Sinks in water.

Air & Water Reactions

Reacts with water slowly forming heavy scum and liberating carbon dioxide gas. Dangerous pressure can build up if container is sealed.

Reactivity Profile

Polymethylene polyphenyl polyisocyanate reacts with water slowly forming heavy scum and liberating carbon dioxide gas. Dangerous pressure can build up if container is sealed. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence [Wischmeyer 1969].

Hazard

Questionable carcinogen.

Health Hazard

Inhalation causes breathlessness, chest discomfort, and reduced pulmonary function; wheezing, cough, and sputum may also occur. Contact with liquid irritates eyes and skin. Ingestion causes irritation of mouth and stomach.

Fire Hazard

Behavior in Fire: Containers may explode.

Safety Profile

Moderately toxic by ingestion. Mildly toxic by inhalation. Questionable carcinogen with experimental neoplastigenic data by implant route. When heated to decomposition it emits toxic fumes of NOx.

Properties of Polymethylene polyphenyl polyisocyanate

Boiling point:	392 °C5 mm Hg
Density	1.2 g/mL at 25 °C(lit.)
vapor density	8.6 (vs air)
refractive index	n20/D 1.634
Flash point:	>230 °F
storage temp.	Refrigerator, Under inert atmosphere
solubility	DMSO (Sparingly), Ethyl Acetate (Slightly), Methanol (Soluble)
form	Oil
color	Yellow to Orange
Stability:	Stable. Incompatible with strong oxidizing agents, alcohols. May decompose in moist air, or on contact with water.
InChI	InChI=1S/C7H5NO.CH2O/c9-6-8-7-4-2-1-3-5-7;1-2/h1-5H;1H2
IARC	3 (Vol. 19, Sup 7) 1987
EPA Substance Registry System	Polymeric diphenylmethane diisocyanate (9016-87-9)

Safety information for Polymethylene polyphenyl polyisocyanate

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H330:Acute toxicity,inhalation H334:Sensitisation, respiratory H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H351:Carcinogenicity H373:Specific target organ toxicity, repeated exposure
Precautionary Statement Codes	P202:Do not handle until all safety precautions have been read and understood. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.