PF-06650833
Synonym(s):1-[[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxo-2-pyrrolidinyl]methoxy]-7-methoxy-6-isoquinolinecarboxamide;PF-06650833
- CAS NO.：1817626-54-2
- Empirical Formula: C18H20FN3O4
- Molecular Weight: 361.37
- MDL number: MFCD30343869
- Update Date: 2025-10-29 15:43:00
What is PF-06650833?
Biochem/physiol Actions
PF06650833 has been studied for its use in the treatment of Waldenstrom macroglobulinemia, indicated by overproduction of IgM (immunoglobulin M)-producing lymphoplasmacytic cells.
Storage
Store at -20°C
Properties of PF-06650833
| Boiling point: | 621.0±55.0 °C(Predicted) |
| Density | 1.34±0.1 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | DMSO : ≥ 33 mg/mL (91.32 mM) |
| form | powder |
| pka | 13.44±0.70(Predicted) |
| color | white to beige |
Safety information for PF-06650833
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for PF-06650833
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