p-Toluenethiol
Synonym(s):4-Methylthiophenol;4-Mercaptotoluene;p-Tolyl mercaptan, p-Thiocresol;p-Thiocresol;p-Toluenethiol
- CAS NO.：106-45-6
- Empirical Formula: C7H8S
- Molecular Weight: 124.2
- MDL number: MFCD00004851
- EINECS: 203-399-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:26:52
What is p-Toluenethiol?
Chemical properties
White or colorless solid melt
The Uses of p-Toluenethiol
p-Thiocresol is used as a pharmaceutical intermediate.
What are the applications of Application
p-Thiocresol is a benzenethiol
Synthesis Reference(s)
Tetrahedron Letters, 21, p. 1235, 1980 DOI: 10.1016/S0040-4039(00)71380-3
Safety Profile
Poison by intraperitoneal route. A flammable liquid. When heated to decomposition it emits toxic fumes of SOx. See also a- TOLUENETHIOL and MERCAPTANS.
Purification Methods
Crystallise the thiol from pet ether (b 40-70o). The 2,4-dinitrophenyl thioether has m 103o (from EtOH), and the 2,4-dinitrophenyl sulfone has m 190o (from EtOH). [Beilstein 6 IV 2153.]
Properties of p-Toluenethiol
| Melting point: | 84-86(lit.) |
| Boiling point: | 195 °C(lit.) |
| Density | 1.0220 |
| vapor density | 6.2 (vs air) |
| vapor pressure | 10 mm Hg ( 71 °C) |
| refractive index | 1.5420 (estimate) |
| Flash point: | 155 °F |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Fused Solid |
| pka | pK1:6.52 (25°C) |
| color | White to yellow |
| Water Solubility | slightly soluble |
| Sensitive | Stench |
| Merck | 14,9325 |
| BRN | 605761 |
| Stability: | Smelly, Air Sensitive |
| CAS DataBase Reference | 106-45-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzenethiol, 4-methyl-(106-45-6) |
| EPA Substance Registry System | Benzenethiol, 4-methyl- (106-45-6) |
Safety information for p-Toluenethiol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for p-Toluenethiol
p-Toluenethiol manufacturer
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline 5-Hydroxy-3,9-dimethyl-7H-benzo[c]fluoren-7-one Methyl 4-(acetyloxy)-6-methoxy-1-(4-methoxyphenyl)-2naphthalenecarboxylate 4-Hydroxy-6,7-dimethoxy-1-phenyl-2naphthalenecarboxylic acid (3,5-Dibromophenyl)[4-(trifluoromethyl)phenyl]methanone (4-butoxyphenyl)(4-fluorophenyl)methanone (4-Bromophenyl)(3,4-dimethoxyphenyl)methanone Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide 4-Ethyl-4-hydroxy-1,4,7,8-tetrahydro-3H,10H-spiro[pyrano[3,4-f]indolizine-6,2'-[1,3]dioxolane]-3,10-dione (E)-N'-(2-cyano-4-nitrophenyl)- N,N-dimethylformimidamide 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid Benzyl-N,4-dimethylpiperidine-3- amine dihydrochloride 5-bromopyridin-2-amine 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3-chlorobenzyl cyanide 3,4 Dimethoxy BenzylcyanideRelated products of tetrahydrofuran
You may like
-
106-45-6 4-Thiocresol 98%View Details
106-45-6 -
106-45-6 p-Thiocresol, 98% 99%View Details
106-45-6 -
p-Toluenethiol CAS 106-45-6View Details
106-45-6 -
4-Methylthiophenol CAS 106-45-6View Details
106-45-6 -
4-Hydroxy-6-methyl-1-(4-methylphenyl)-2naphthalenecarboxylic acid 98+View Details
101894-09-1 -
83883-25-4 98+View Details
83883-25-4 -
54598-15-1 4,5,7-Trimethyl-2(1H)-quinolinone 98+View Details
54598-15-1 -
4-(6-HYDROXYHEXYLOXY)BENZOIC ACID 83883-25-4 98+View Details
83883-25-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.