Oxyfedrine
- CAS NO.：15687-41-9
- Empirical Formula: C19H23NO3
- Molecular Weight: 313.39
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 09:27:42
What is Oxyfedrine?
Originator
Ildamen,Homburg,W. Germany ,1966
The Uses of Oxyfedrine
Oxyfedrine acts as a vasodilator affecting the coronary base flow.
Definition
ChEBI: Oxyfedrine is an aromatic ketone.
Manufacturing Process
45 grams of m-methoxy acetophenone, 8 grams of paraformaldehyde and 30.2 grams of 1 norephedrine were mixed with about 135 cc of isopropanol HCl solution to provide a pH of 4 and the mixture refluxed for 4 hours. The reaction mixture was cooled and the crystals filtered off on a suction filter. 3[1-phenyl-1-hydroxypropyl-(2)-amino]-1-(m-methoxyphenyl)-propanone-(1) HCl was obtained which after recrystallization from methanol had a MP of 190° to 193°C.
Therapeutic Function
Coronary vasodilator
Properties of Oxyfedrine
| Melting point: | 107-109°C |
| Boiling point: | 475.2±28.0 °C(Predicted) |
| Density | 1.122±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly), Toluene (Slightly) |
| pka | 13.90±0.20(Predicted) |
| form | Solid |
| color | White to Off-White |
| Stability: | Hygroscopic, Moisture Sensitive |
Safety information for Oxyfedrine
Computed Descriptors for Oxyfedrine
New Products
3-azanyl-3-phenyl-propanoic acid 3-AMINO-3-(2-METHYLPHENYL)PROPANOIC ACID 3-AMINO-3-M-TOLYL-PROPIONIC ACID Nitroso Irbesartan N-Nitroso Nortriptyline 1-nitro-3,5-dimethyl adamantine (NMEM) 3-(2-aminoethyl) benzene sulfonamide Nabumetone Impurity 5 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-one 4-dimethylaminopyridine 3-Bromo-2-Methyl-5-Nitropyridine 2-Chloro Isonicotinic acid methyl ester 2-(Ethoxymethylene)propanedinitrile 5-Bromo-3-Methyl-2-Pyridinecarboxylic acid 5-Chloro-pyridine-2-carboxylic acid amideRelated products of tetrahydrofuran
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