O-PHOSPHO-L-THREONINE
Synonym(s):( S) -2-Amino-3-hydroxybutanoic acid 3-phosphate;L -Threonine O-phosphate
- CAS NO.：1114-81-4
- Empirical Formula: C4H10NO6P
- Molecular Weight: 199.1
- MDL number: MFCD00069578
- EINECS: 214-217-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 23:59:56
What is O-PHOSPHO-L-THREONINE?
Definition
ChEBI: O-phospho-L-threonine is a L-threonine derivative phosphorylated at the side-chain hydroxy function. It has a role as an Escherichia coli metabolite. It is a L-threonine derivative, a non-proteinogenic L-alpha-amino acid and an O-phosphoamino acid. It is a conjugate acid of an O-phosphonato-L-threonine(2-).
Biochem/physiol Actions
O-Phospho-L-threonine is an amino acid derivative.
Purification Methods
Dissolve the phosphate in the minimum volume of H2O, add charcoal, stir for a few minutes, filter and apply onto a column of Dowex 50W (H+ form), then elute with 2N HCl. Evaporate the eluates under reduced pressure whereby the desired fraction produces crystals of the phosphate which can be recrystallised from H2O/MeOH mixtures and the crystals are then dried in vacuo over P2O5 at ~80o. [de Verdier Acta Chem Scand 7 196 1953, Beilstein 4 IV 3175.]
Properties of O-PHOSPHO-L-THREONINE
| Melting point: | 169 °C |
| Boiling point: | 454.0±55.0 °C(Predicted) |
| Density | 1.671±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | NH4OH 1 M: 0.1 g/mL, clear, colorless |
| pka | 1.73±0.10(Predicted) |
| form | A solid |
| BRN | 1727078 |
Safety information for O-PHOSPHO-L-THREONINE
Computed Descriptors for O-PHOSPHO-L-THREONINE
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![THREONINE PHOSPHATE, L-, [14C(U)]](https://img.chemicalbook.in/StructureFile/ChemBookStructure7/GIF/CB4473657.gif)
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