N,N-Dimethylethylenediamine
Synonym(s):2-(Dimethylamino)ethylamine;2-(Dimethylamino)ethylamine, 1-Amino-2-dimethylaminoethane;DMEN;N,N-Dimethylethylenediamine
- CAS NO.:108-00-9
- Empirical Formula: C4H12N2
- Molecular Weight: 88.15
- MDL number: MFCD00008175
- EINECS: 203-541-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:40
What is N,N-Dimethylethylenediamine?
Description
N,N'-Dimethylethylenediamine is used in DNA binding effect. It is used to enhance the adsorption of carbon dioxide. It acts as a ligand and form coordination complex such as dinitrato(N,N'-dimethyl-1,2-ethanediamine)copper(II) and dichloro(1,4-bis-(diphenyl phosphino)butane)-(1,2-ethylenediamine)ruthenium(II).
Chemical properties
clear colorless to pale yellow liquid
The Uses of N,N-Dimethylethylenediamine
It finds its application as an intermediate in the synthesis of Cefotiam. It is also used as a catalyst in the synthesis of allylic nitro compounds.
The Uses of N,N-Dimethylethylenediamine
N,N-Dimethylethylenediamine is a bidentate ligand that can be used:
- To synthesize Schiff base ligands to prepare their zinc alkyl and zinc alkoxide complexes that initiate ring-opening polymerization of lactides.
- As a ligand to prepare copper azido polymers.
- In the synthesis of naphthalimides such as amonafide, an antitumor agent.
- As the receptor in building fluorescent signaling systems to perturb the photoinduced intramolecular electron transfer (PET) process from the nitrogen lone-pair to the fluorophore.
Solubility in organics
N,N'-Dimethylethylenediamine is miscible with chloroform and dichloromethane. Incompatible with acids, chlorides, anhydrides, strong oxidising agents and carbon dioxide.
Properties of N,N-Dimethylethylenediamine
| Melting point: | -70 °C |
| Boiling point: | 104-106 °C (lit.) |
| Density | 0.807 g/mL at 20 °C (lit.) |
| vapor pressure | 0.35 psi ( 20 °C) |
| refractive index | n |
| Flash point: | 75 °F |
| storage temp. | Store below +30°C. |
| form | Liquid |
| pka | 9.59±0.10(Predicted) |
| color | Clear colorless to pale yellow |
| PH | 11.4 (10g/l, H2O, 20℃) |
| explosive limit | 1.3-10.8%(V) |
| Water Solubility | MISCIBLE |
| Sensitive | Hygroscopic |
| BRN | 605279 |
| CAS DataBase Reference | 108-00-9(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,2-Ethanediamine, N,N-dimethyl-(108-00-9) |
| EPA Substance Registry System | 1,2-Ethanediamine, N,N-dimethyl- (108-00-9) |
Safety information for N,N-Dimethylethylenediamine
| Signal word | Danger |
| Pictogram(s) |
![]() Flame Flammables GHS02 ![]() Corrosion Corrosives GHS05 ![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H225:Flammable liquids H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N,N-Dimethylethylenediamine
New Products
DL-beta-(3-Bromophenyl)alanine Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine(RM for Indian lab) N,N CARBONYL DIIMIDAZOLE Levothyroxine Impurity-F Montelukast EP Impurity-D/Montelukast USP Related Compound C Atorvastatin FXA Impurity/Atorvastatin Cyclic 6-Hydroxy Impurity Sodium Salt Isosulfan blue Keto N-Oxide Impurity Ivermectin Impurity F N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene CSA (DL-10-Camphorsulfonic Acid) 2-Hydroxy-4-methylnicotinic acid 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioateRelated products of tetrahydrofuran








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