N,N-Diethylethylenediamine

Synonym(s):2-(Diethylamino)ethylamine, 1-Amino-2-(diethylamino)ethane;2-Diethylaminoethylamine;N,N-Diethylethylenediamine

CAS NO.：100-36-7
Empirical Formula: C6H16N2
Molecular Weight: 116.2
MDL number: MFCD00008176
EINECS: 202-844-7
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-01 16:59:24

What is N,N-Diethylethylenediamine?

Chemical properties

CLEAR COLORLESS TO LIGHT YELLOW LIQUID

The Uses of N,N-Diethylethylenediamine

N,N-Diethylethylenediamine is used in the syntheses of anti-malarials. In addition, it has been seem to induce apoptosis through a caspase-3 dependent pathway.

The Uses of N,N-Diethylethylenediamine

N,N-Diethylethylenediamine was used in the oxidative amidation of hydrogen phosphonate diesters in the synthesis of oligonucleotides. It is also used to develop melanin targeted PET and single-photon emission computed tomography (SPECT) imaging agents for melanoma.

Flammability and Explosibility

Flammable

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion and skin contact. A slun and severe eye irritant. Flammable liquid when exposed to heat or flame; can react with oxidzing materials. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of NOx. See also AMINES.

Properties of N,N-Diethylethylenediamine

Melting point:	<-70°C
Boiling point:	145-147 °C(lit.)
Density	0.827 g/mL at 25 °C(lit.)
vapor pressure	5.33hPa at 20℃
refractive index	n20/D 1.436(lit.)
Flash point:	87 °F
storage temp.	Store below +30°C.
solubility	soluble in Methanol, Water
pka	pK1:7.70(+2);pK2:10.46(+1) (25°C)
form	Liquid
color	Clear colorless to light yellow
explosive limit	0.7-8.4%(V)
Water Solubility	MISCIBLE
Sensitive	Air Sensitive
BRN	605299
CAS DataBase Reference	100-36-7(CAS DataBase Reference)
NIST Chemistry Reference	1,2-Ethanediamine, N,N-diethyl-(100-36-7)
EPA Substance Registry System	N,N-Diethylethylenediamine (100-36-7)

Safety information for N,N-Diethylethylenediamine

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H226:Flammable liquids H311:Acute toxicity,dermal H314:Skin corrosion/irritation H332:Acute toxicity,inhalation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.