N,N-Diethylethylenediamine
Synonym(s):2-(Diethylamino)ethylamine, 1-Amino-2-(diethylamino)ethane;2-Diethylaminoethylamine;N,N-Diethylethylenediamine
- CAS NO.:100-36-7
- Empirical Formula: C6H16N2
- Molecular Weight: 116.2
- MDL number: MFCD00008176
- EINECS: 202-844-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:55
What is N,N-Diethylethylenediamine?
Chemical properties
CLEAR COLORLESS TO LIGHT YELLOW LIQUID
The Uses of N,N-Diethylethylenediamine
N,N-Diethylethylenediamine is used in the syntheses of anti-malarials. In addition, it has been seem to induce apoptosis through a caspase-3 dependent pathway.
The Uses of N,N-Diethylethylenediamine
N,N-Diethylethylenediamine was used in the oxidative amidation of hydrogen phosphonate diesters in the synthesis of oligonucleotides. It is also used to develop melanin targeted PET and single-photon emission computed tomography (SPECT) imaging agents for melanoma.
Flammability and Explosibility
Flammable
Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion and skin contact. A slun and severe eye irritant. Flammable liquid when exposed to heat or flame; can react with oxidzing materials. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of NOx. See also AMINES.
Properties of N,N-Diethylethylenediamine
| Melting point: | <-70°C |
| Boiling point: | 145-147 °C(lit.) |
| Density | 0.827 g/mL at 25 °C(lit.) |
| vapor pressure | 5.33hPa at 20℃ |
| refractive index | n |
| Flash point: | 87 °F |
| storage temp. | Store below +30°C. |
| solubility | soluble in Methanol, Water |
| pka | pK1:7.70(+2);pK2:10.46(+1) (25°C) |
| form | Liquid |
| color | Clear colorless to light yellow |
| explosive limit | 0.7-8.4%(V) |
| Water Solubility | MISCIBLE |
| Sensitive | Air Sensitive |
| BRN | 605299 |
| CAS DataBase Reference | 100-36-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,2-Ethanediamine, N,N-diethyl-(100-36-7) |
| EPA Substance Registry System | N,N-Diethylethylenediamine (100-36-7) |
Safety information for N,N-Diethylethylenediamine
| Signal word | Danger |
| Pictogram(s) |
![]() Flame Flammables GHS02 ![]() Corrosion Corrosives GHS05 ![]() Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H226:Flammable liquids H311:Acute toxicity,dermal H314:Skin corrosion/irritation H332:Acute toxicity,inhalation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N,N-Diethylethylenediamine
| InChIKey | PQZTVWVYCLIIJY-UHFFFAOYSA-N |
N,N-Diethylethylenediamine manufacturer
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