Naphazoline nitrate
Synonym(s):2-(1-Naphthylmethyl)imidazoline nitrate
- CAS NO.：5144-52-5
- Empirical Formula: C14H15N3O3
- Molecular Weight: 273.29
- MDL number: MFCD00014316
- EINECS: 225-915-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:19:22
What is Naphazoline nitrate ?
Chemical properties
White or almost white, crystalline powder.
The Uses of Naphazoline nitrate
antihistamine
What are the applications of Application
Naphazoline Nitrate is a compound which produces inotropic effects via a-adrenoceptor stimulation
Indications
Naphazoline hydrochloride and naphazoline nitrate are white or almost white crystalline powders soluble 1 in 6 and 1 in 36 water, respectively. These are potent sympathomimetic vasoconstrictors with a direct alpha-adrenergic receptor stimulatory action, and may be used as topical decongestants in 0.05% or 0.1% eyedrops. Frequent application of these solutions will produce a reactive hyperaemia. Instillation should not be repeated in less than 4-6 hours to avoid this rebound congestion.
Naphazoline eyedrops cause slight mydriasis and are contra-indicated in patients with actual or suspected closed-angle glaucoma.
Although not administered systemically, topical application of naphazoline has resulted in systemic absorption, and it is readily absorbed from the gastro-intestinal tract (Martindale, 1977).
Definition
ChEBI: Naphazoline nitrate is a member of naphthalenes.
Properties of Naphazoline nitrate
| Melting point: | 167-170 °C |
| solubility | Sparingly soluble in water, soluble in ethanol (96 per cent). |
| form | neat |
| form | Solid |
| color | White to off-white |
| Sensitive | Hygroscopic |
| BRN | 3779329 |
| CAS DataBase Reference | 5144-52-5(CAS DataBase Reference) |
Safety information for Naphazoline nitrate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for Naphazoline nitrate
| InChIKey | ZAHXYMFVNNUHCP-UHFFFAOYSA-N |
Naphazoline nitrate manufacturer
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