Sertaconazole nitrate
- CAS NO.：99592-39-9
- Empirical Formula: C20H15Cl3N2OS.HNO3
- Molecular Weight: 500.78
- MDL number: MFCD00918063
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-29 17:45:46
What is Sertaconazole nitrate?
Description
Sertaconazole nitrate is a new broad spectrum imidazole antifungal agent introduced in a topical formulation for the treatment of cutaneous infections. Its mechanism of action is the inhibition of ergosterol synthesis and interference with the permeability of fungus cell membranes. An oral formulation is currently under investigation for the treatment of bucco-pharyngeal fungal infections.
Chemical properties
Off-White Solid
Originator
Ferrer (Spain)
The Uses of Sertaconazole nitrate
An imidazole antifungal agent, inhibits the synthesis of ergosterol, an essential cell wall component of fungi.
The Uses of Sertaconazole nitrate
Antibacterial;ergosterol synthesis inhibitor
brand name
Dermofix; Zalain
Properties of Sertaconazole nitrate
| Melting point: | 158-160° |
| storage temp. | -20°C |
| solubility | DMSO: soluble20mg/mL, clear |
| form | powder |
| pka | pKb: 7.26(at 25℃) |
| color | white to beige |
Safety information for Sertaconazole nitrate
| Signal word | Warning |
| Pictogram(s) |
 Health Hazard GHS08 |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for Sertaconazole nitrate
| InChIKey | HAAITRDZHUANGT-UHFFFAOYSA-N |
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