N(4)-methylcytidine

CAS NO.：10578-79-7
Empirical Formula: C10H15N3O5
Molecular Weight: 257.24
MDL number: MFCD23701766
SAFETY DATA SHEET (SDS)
Update Date: 2026-07-16 07:06:08

What is N(4)-methylcytidine?

Description

N4-Methylcytidine is a nucleoside analogue that inhibits synthesis of human mitochondrial DNA by inhibiting bacterial enzyme uridine-cytidine kinase, which converts uridine to cytidine in the mitochondria. N4-Methylcytidine has been shown to be potent against viruses such as HIV and herpes simplex virus type 1 (HSV-1) in cell culture studies. This antiviral effect is due to the interference with viral dna replication and protein synthesis by preventing incorporation of uracil into dna and ribosomal RNA.

Definition

ChEBI: N4-Methylcytidine is a pyrimidine nucleoside.

Properties of N(4)-methylcytidine

Melting point:	202-203 °C(Solv: ethanol (64-17-5))
Boiling point:	504.2±60.0 °C(Predicted)
Density	1.69±0.1 g/cm3(Predicted)
storage temp.	2-8°C(protect from light)
solubility	Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form	Solid
pka	13.48±0.70(Predicted)
color	Off-White to Beige
Stability:	Hygroscopic

Safety information for N(4)-methylcytidine

Signal word	Danger
Pictogram(s)	Health Hazard GHS08
GHS Hazard Statements	H304:Aspiration hazard H413:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P331:Do NOT induce vomiting. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P405:Store locked up.

Computed Descriptors for N(4)-methylcytidine

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