N-Succinimidyl S-Acetylthioglycolate

Chemical properties

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The Uses of N-Succinimidyl S-Acetylthioglycolate

N-Succinimidyl S-Acetylthioglycolate can be used as Thiolating reagent for primary amines; thiol can be deprotected under mild conditions and be useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

The Uses of N-Succinimidyl S-Acetylthioglycolate

Reacts with primary amines to add protected sulfhydryls.

The Uses of N-Succinimidyl S-Acetylthioglycolate

Thiolating reagent for primary amines; thiol can be deprotected under mild conditions. Typically, couples initially to a molecule containing primary amine by amide bond buffered at pH 7.5. Deprotection may be accomplished with 0.05 M hydroxylamine at neutral pH. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

What are the applications of Application

N-Succinimidyl-S-acetylthioacetate is reacts with 1 amines to add protected thiol groups