N-NITROSO-N-METHYLURETHANE

Chemical properties

Yellow Oil

The Uses of N-NITROSO-N-METHYLURETHANE

N-Methyl-N-nitrosourethane is a nitrosamide which causes chromosomal damage in HeLa cells. It is also used in the synthesis of antifungal agents such as azoxybacillin.

Definition

ChEBI: N-Nitroso-N-methylurethane is a carboxylic ester.

General Description

Solid.

Reactivity Profile

N-NITROSO-N-METHYLURETHANE is a N-nitrosated carbamate ester. Incompatible with strong acids and bases. Especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen may be produced by the combination with active metals or nitrides Incompatible with oxidizing acids, peroxides, and hydroperoxides.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by inhalation. Experimental reproductive effects. Mutation data reported. Has been implicated as a transplacental brain carcinogen. Combustible when exposed to heat, sparks, open flame, and powerful oxidizers. Explodes when heated. A storage hazard. When heated to decomposition it emits toxic fumes of NOx.