N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE
Synonym(s):Elastase Substrate I, Colorimetric - CAS 70967-90-7 - Calbiochem;Methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide - CAS 70967-90-7 - Calbiochem;N-(Methoxysuccinyl)-L -alanyl-L -alanyl-L -prolyl-L -valine 4-nitroanilide;N-(Methoxysuccinyl)-Ala-Ala-Pro-Val 4-nitroanilide
- CAS NO.：70967-90-7
- Empirical Formula: C27H38N6O9
- Molecular Weight: 590.63
- MDL number: MFCD00077137
- EINECS: 232-670-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-11 16:31:51
What is N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE?
Description
Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy pathogens. Evaluating these enzymes is helpful to understanding inflammatory autoimmune processes. MeOSuc-AAPV-pNA is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3, but not cathepsin G or chymotrypsin. Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm.
The Uses of N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE
N-Methoxysuccinyl-Ala-Ala-Pro-Val p-Nitroanilide is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3 but not cathespin.
What are the applications of Application
MeOSuc-AAPV-pNA, Chromogenic Substrate is a sensitive PR3 and neutrophil elastase chromogenic substrate
Properties of N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE
| Melting point: | 203-205°C |
| Boiling point: | 958.4±65.0 °C(Predicted) |
| Density | 1.297±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMF: 25 mg/mL, clear, light yellow |
| form | Off-white solid |
| pka | 13.29±0.20(Predicted) |
| color | White to Off-White |
| BRN | 6266359 |
Safety information for N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE
Computed Descriptors for N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE
New Products
Tridecanoic acid 3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 2-Bromo-5-Iodopyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 1-Fluorocyclopropanecarboxylic Acid 2-(tert-Butoxycarbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid (S)-3-Hydroxypyrrolidine hydrochloride Dimethyl (2,2-dihydroxy-3,3-difluoro-2-oxoheptyl)phosphonate Lead tetraacetate 7-iodopyrrolo[2,1-f][1,2,4]triazin-4-amine 5-Phenyl-[1,3,4]-thiadiazol-2-amine 2-Chloro-6-nitro benzothiazole N-(4-Bromophenyl)-2-chloroacetamide 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinolineRelated products of tetrahydrofuran
You may like
-
N-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide 98% (HPLC) CAS 70967-90-7View Details
70967-90-7 -
Elastase Substrate I, Colorimetric CAS 70967-90-7View Details
70967-90-7 -
N-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide CAS 70967-90-7View Details
70967-90-7 -
Methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide CAS 70967-90-7View Details
70967-90-7 -
2-Bromo-4-nitropyridine-N-oxide 52092-43-0 98%View Details
52092-43-0 -
4, 4'-Ditolylamine (or) 4,4-Dimethyl Diphenylamine 620-93-9 98%View Details
620-93-9 -
2-Bromo-5-Chloropyridine 98%View Details
40473-01-6 -
Eperisone Hydrochloride APIView Details
56839-43-1