N-Boc-propargylamine

CAS NO.：92136-39-5
Empirical Formula: C8H13NO2
Molecular Weight: 155.19
MDL number: MFCD07367245
SAFETY DATA SHEET (SDS)
Update Date: 2025-09-25 17:15:13

What is N-Boc-propargylamine?

Chemical properties

Pale Yellow Low Melting Solid

The Uses of N-Boc-propargylamine

N-Boc-propargylamine is used in the preparation of triazolobenzylidene-thiazolopyrimidines which act as CDC25 phosphatase inhibitors. Also used in the synthesis of β-glucan polysaccharide analogs.

The Uses of N-Boc-propargylamine

N-Boc-propargylamine is used to prepare triazolobenzylidene-thiazolopyrimidines. which act as CDC25 phosphatase inhibitors. Further, it is used for the synthesis of beta-glucan polysaccharide analogs. In addition to this, it is involved in the Pauson-Khand (PK) reaction of norbornadiene and N-Boc-propargylamine to prepare 4,5-disubstituted cyclopentenones .

What are the applications of Application

N-Boc-propargylamine is N-Boc-propargylamine is used in the preparation of triazolobenzylidene-thiazolopyrimidines which act as CDC25 phosphatase inhibitors. Also used in the synthesis of β-glucan polysaccharide analogs.

Properties of N-Boc-propargylamine

Melting point:	40-44 °C
Boiling point:	170°C/14mmHg(lit.)
Density	0.990±0.06 g/cm3(Predicted)
Flash point:	93°(199°F)
storage temp.	2-8°C
solubility	Soluble in chloroform.
form	Solid
pka	11.24±0.46(Predicted)
color	Pale Yellow to Dark Yellow
Sensitive	Moisture Sensitive

Safety information for N-Boc-propargylamine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.