N-Acetyl-L-methionine
- CAS NO.：65-82-7
- Empirical Formula: C7H13NO3S
- Molecular Weight: 191.25
- MDL number: MFCD00064441
- EINECS: 200-617-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-05 14:33:18
What is N-Acetyl-L-methionine?
Chemical properties
white crystals
The Uses of N-Acetyl-L-methionine
N-Acetyl-L-methionine (CAS# 65-82-7) has been useful in the study of metabolic phenotypes of standard and cold-?stored platelets.
Definition
ChEBI: An L-methionine derivative that is L-methionine in which one of the amine hydrogens is substituted by an acetyl group.
Safety Profile
Poison by intravenous route. When heated to decomposition emits toxic fumes of NOX,.
Purification Methods
Crystallise N-acetyl-L-methionine from Me2CO, H2O or EtOAc. Dry it in a vacuum over P2O5. Its solubility at 25o in H2O is 30.7%, and in Me2CO it is 29.5%. [Mitzi & Schueter Biochim Biophys Acta 27 168 1958, Birnbaum et al. J Biol Chem 194 455 1952, Beilstein 4 IV 3206.]
Properties of N-Acetyl-L-methionine
| Melting point: | 103-106 °C(lit.) |
| Boiling point: | 235 °C(Press: 12 Torr) |
| alpha | -20 º (c=4 H2O) |
| Density | 1.2684 (rough estimate) |
| refractive index | -21 ° (C=1, H2O) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | methanol: soluble100mg/mL, clear, colorless |
| form | Solid |
| pka | 3.50±0.10(Predicted) |
| color | White to Off-White |
| optical activity | [α]20/D -21.0±1.0°, c = 1% in H2O |
| Merck | 14,96 |
| BRN | 1725552 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 65-82-7(CAS DataBase Reference) |
| NIST Chemistry Reference | N-acetylmethionine(65-82-7) |
| EPA Substance Registry System | L-Methionine, N-acetyl- (65-82-7) |
Safety information for N-Acetyl-L-methionine
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for N-Acetyl-L-methionine
| InChIKey | XUYPXLNMDZIRQH-LURJTMIESA-N |
N-Acetyl-L-methionine manufacturer
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