N-Acetyl-DL-phenylalanine
- CAS NO.：2901-75-9
- Empirical Formula: C11H13NO3
- Molecular Weight: 207.23
- MDL number: MFCD00063157
- EINECS: 220-793-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-19 17:28:17
What is N-Acetyl-DL-phenylalanine?
Originator
Afalanine ,Sankyo
The Uses of N-Acetyl-DL-phenylalanine
N-Acetyl-DL-phenylalanine is an antidepressant, used to prevent kidney damage.
Definition
ChEBI: The N-acetyl derivative of phenylalanine.
Manufacturing Process
The phenylalanine was dispersed in water. A 1 N aqueous solution of sodium
hydroxide was slowly added to this dispersion, and the pH of the solution
reached a value of 7-8.
Then acetylbromide was dissolved in this solution, to give a Nacetylphenylalanine.
Therapeutic Function
Antidepressant
Synthesis Reference(s)
Tetrahedron Letters, 31, p. 243, 1990 DOI: 10.1016/S0040-4039(00)94382-X
Properties of N-Acetyl-DL-phenylalanine
| Melting point: | 152.0 to 156.0 °C |
| Boiling point: | 453.9±38.0 °C(Predicted) |
| Density | 1.199±0.06 g/cm3(Predicted) |
| RTECS | SQ7321132 |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| form | Powder |
| pka | 3.56±0.10(Predicted) |
| color | Off-white |
| λmax | 280nm(lit.) |
| CAS DataBase Reference | 2901-75-9(CAS DataBase Reference) |
Safety information for N-Acetyl-DL-phenylalanine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N-Acetyl-DL-phenylalanine
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