N-(3-Trifluoromethylphenyl)piperazine
- CAS NO.：15532-75-9
- Empirical Formula: C11H13F3N2
- Molecular Weight: 230.23
- MDL number: MFCD00005959
- EINECS: 239-574-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:18
What is N-(3-Trifluoromethylphenyl)piperazine?
Chemical properties
clear colourless to yellow slightly viscous liquid
The Uses of N-(3-Trifluoromethylphenyl)piperazine
1-[3-(Trifluoromethyl)phenyl]piperazine is used in preparation of (Piperazinylethyl)cyclohexanamide derivatives and used as treatment or prevention of D3 and/or 5HT-2 receptor diseases.
Definition
ChEBI: A N-arylpiperazine that is piperazine substituted by a 3-(trifluoromethyl)phenyl group at position 1. A serotonergic agonist used as a recreational drug.
Synthesis Reference(s)
Tetrahedron Letters, 37, p. 319, 1996 DOI: 10.1016/0040-4039(95)02162-0
Properties of N-(3-Trifluoromethylphenyl)piperazine
| Boiling point: | 100-102°C 0,1mm |
| Density | 1.226 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | -20°C |
| form | neat |
| pka | 8.88±0.10(Predicted) |
| Sensitive | Air Sensitive |
| BRN | 614217 |
| CAS DataBase Reference | 15532-75-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Piperazine, 1-[3-(trifluoromethyl)phenyl]-(15532-75-9) |
Safety information for N-(3-Trifluoromethylphenyl)piperazine
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H314:Skin corrosion/irritation H318:Serious eye damage/eye irritation H370:Specific target organ toxicity, single exposure |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for N-(3-Trifluoromethylphenyl)piperazine
N-(3-Trifluoromethylphenyl)piperazine manufacturer
Cns Chemicals
Hyderabad
Phone:91-9381957258
Whatsapp: 91-9381957258
product: N-[3-(Trifluoromethyl)-phenyl]-piperazine
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