N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
- CAS NO.：103878-83-7
- Empirical Formula: C8H10ClN3O.HCl
- Molecular Weight: 0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-08-20 20:20:01
What is N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid?
The Uses of N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
Treatment of Alzheimer’s disease.
The Uses of N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
Lazabemide Hydrochloride is a reversible and selective inhibitor of MAO-A and MAO-B, both of which oxidatively deaminate neurotransmitter and xenobiotic amines.
Definition
ChEBI: Lazabemide hydrochloride is a pyridinecarboxamide.
What are the applications of Application
Lazabemide hydrochloride is a selective and reversible monoamine oxidase B inhibitor
brand name
Tempium (Hoffmann-LaRoche).
Biological Activity
Selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC 50 values are 0.03 and > 100 μ M for MAO-B and MAO-A respectively). Inhibits monoamine uptake at high concentrations (IC 50 values are 86, 123 and > 500 μ M for noradrenalin, serotonin and dopamine uptake respectively).
Storage
Desiccate at RT
Properties of N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
| Melting point: | 193-195° |
| storage temp. | Desiccate at RT |
| solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
| form | Powder |
| pka | 8.9(at 25℃) |
Safety information for N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
Computed Descriptors for N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
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