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HomeProduct name listN-[2-(3,4-DIHYDROXYPHENYL)ETHYL]OCTADECANAMIDE

N-[2-(3,4-DIHYDROXYPHENYL)ETHYL]OCTADECANAMIDE

N-[2-(3,4-DIHYDROXYPHENYL)ETHYL]OCTADECANAMIDE Structural

What is N-[2-(3,4-DIHYDROXYPHENYL)ETHYL]OCTADECANAMIDE?

The Uses of N-[2-(3,4-DIHYDROXYPHENYL)ETHYL]OCTADECANAMIDE

STEARDA is a novel, endogenous capsaicin-like lipid that produces hyperalgesia.

What are the applications of Application

STEARDA is a 5-LO (5-lipoxygenase) inhibitor

Definition

ChEBI: N-stearoyl dopamine is a carboxamide. It is functionally related to a dopamine.

Biological Activity

Endogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. Inactive at TRPV1 and CB 1 receptors (at concentrations up to 5 μ M) and does not inhibit AMT or FAAH (IC 50 > 25 μ M). However, potentiates TRPV1-mediated effects of NADA in vitro and in vivo ; enhances effects on intracellular Ca 2+ (EC 50 lowered 3-fold) and nociception. Also inhibits arachidonate 5-lipoxygenase (IC 50 = 16 nM).

Properties of N-[2-(3,4-DIHYDROXYPHENYL)ETHYL]OCTADECANAMIDE

storage temp.  Store at +4°C
solubility  Soluble to 5 mM in ethanol with gentle warming
form  Powder

Safety information for N-[2-(3,4-DIHYDROXYPHENYL)ETHYL]OCTADECANAMIDE

Computed Descriptors for N-[2-(3,4-DIHYDROXYPHENYL)ETHYL]OCTADECANAMIDE

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