MRS 1220
Synonym(s):9-Chloro-2-(2-furanyl)-5-((phenylacetyl)amino)-[1,2,4]triazolo[1,5-c]quinazoline
- CAS NO.：183721-15-5
- Empirical Formula: C21H14ClN5O2
- Molecular Weight: 403.82
- MDL number: MFCD01321046
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-16 07:06:08
What is MRS 1220?
The Uses of MRS 1220
MRS 1220 is a highly potent and selective human Adenosine A3-R antagonist.
What are the applications of Application
MRS 1220 is a highly potent and selective human Adenosine A3-R antagonist
Definition
ChEBI: N-[9-chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-2-phenylacetamide is a member of quinazolines.
Biological Activity
A potent and highly selective antagonist at the human A 3 adenosine receptor (K i values are 0.65, 305, and 52 nM at hA 3 , rA 1 and rA 2A respectively. Displays an IC 50 value > 1 μ M for inhibition of binding to rat A 3 receptors).
Storage
Store at RT
Properties of MRS 1220
| Density | 1.49±0.1 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | DMSO: 2 mg/mL |
| form | solid |
| pka | 8.17±0.46(Predicted) |
| color | white |
Safety information for MRS 1220
Computed Descriptors for MRS 1220
New Products
9-Mesityl-10-methylacridinium perchlorate Sulfapyridine Fmoc-OSu (R)-(-)-2-Amino-1-propanol Cyclobutanone 5-bromo-4-fluoro-2-nitrobenzaldehyde 4 pentyn 1 ol N-Vinylformamide Phenethyl cinnamate Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 4-Nitrobenzotrifluoride 2-Pentyn-1-oL N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran
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