MONOETHYLGLYCINEXYLIDIDE
Synonym(s):MEGX;MGEX;Monoethylglycinexylidide;N-(2,6-dimethylphenyl)-2-(ethylamino)acetamide;Norlidocaine
- CAS NO.：7728-40-7
- Empirical Formula: C12H18N2O
- Molecular Weight: 206.28
- MDL number: MFCD00098991
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 02:55:40
What is MONOETHYLGLYCINEXYLIDIDE?
Chemical properties
White Solid
The Uses of MONOETHYLGLYCINEXYLIDIDE
A metabolite of Lidocaine (L397800).
The Uses of MONOETHYLGLYCINEXYLIDIDE
MEGX has been used in an approach to improve the yield of N-dealkylated lidocaine.
Definition
ChEBI: Amino acid amide formed from 2,6-dimethylaniline and N-ethylglycine components; an active metabolite of lidocaine, formed by oxidative deethylation. Used as an indicator of hepatic function.
Biochem/physiol Actions
Monoethylglycinexylidide (MEGX) is an active metabolite of lidocaine.
Properties of MONOETHYLGLYCINEXYLIDIDE
| Melting point: | 242-245°C |
| Boiling point: | 335.6±30.0℃ (760 Torr) |
| Density | 1.047±0.06 g/cm3 (20 ºC 760 Torr) |
| Flash point: | 127.8±24.7℃ |
| storage temp. | 2-8°C |
| solubility | H2O: soluble10mg/mL, clear |
| form | powder |
| pka | pKa 8.04(H2O,t =25±0.2,I=0.01(NaCl)) (Uncertain) |
| color | white to beige |
Safety information for MONOETHYLGLYCINEXYLIDIDE
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for MONOETHYLGLYCINEXYLIDIDE
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