MONOETHYLGLYCINEXYLIDIDE
Synonym(s):MEGX;MGEX;Monoethylglycinexylidide;N-(2,6-dimethylphenyl)-2-(ethylamino)acetamide;Norlidocaine
- CAS NO.：7728-40-7
- Empirical Formula: C12H18N2O
- Molecular Weight: 206.28
- MDL number: MFCD00098991
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:25:00
What is MONOETHYLGLYCINEXYLIDIDE?
Chemical properties
White Solid
The Uses of MONOETHYLGLYCINEXYLIDIDE
A metabolite of Lidocaine (L397800).
The Uses of MONOETHYLGLYCINEXYLIDIDE
MEGX has been used in an approach to improve the yield of N-dealkylated lidocaine.
Definition
ChEBI: Amino acid amide formed from 2,6-dimethylaniline and N-ethylglycine components; an active metabolite of lidocaine, formed by oxidative deethylation. Used as an indicator of hepatic function.
Biochem/physiol Actions
Monoethylglycinexylidide (MEGX) is an active metabolite of lidocaine.
Properties of MONOETHYLGLYCINEXYLIDIDE
| Melting point: | 242-245°C |
| Boiling point: | 335.6±30.0℃ (760 Torr) |
| Density | 1.047±0.06 g/cm3 (20 ºC 760 Torr) |
| Flash point: | 127.8±24.7℃ |
| storage temp. | 2-8°C |
| solubility | H2O: soluble10mg/mL, clear |
| form | powder |
| pka | pKa 8.04(H2O,t =25±0.2,I=0.01(NaCl)) (Uncertain) |
| color | white to beige |
Safety information for MONOETHYLGLYCINEXYLIDIDE
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for MONOETHYLGLYCINEXYLIDIDE
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline (4-Bromophenyl)(3-methoxyphenyl)methanone 4,5,7-Trimethyl-2(1H)-quinolinone 4-(6-HYDROXYHEXYLOXY)BENZOIC ACID 4-Hydroxy-6-methyl-1-(4-methylphenyl)-2naphthalenecarboxylic acid 2,6-Piperidinedione, 3-hydroxy-1-[(4-methoxyphenyl)methyl]- NA Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 4 - fluoro- 2 - methoxy- 5 - nitroaniline 1-(2-amino-5-hydroxy phenyl)propan-1-one tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 5-bromo-2-chloro-N- cyclopentylpyrimidin-4- amine 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3-chlorobenzyl cyanide 3,4 Dimethoxy BenzylcyanideRelated products of tetrahydrofuran
![LIDOCAINE HYDROCHLORIDE, [CARBONYL-14C]](https://img.chemicalbook.in/CAS/GIF/40252-00-4.gif)
![N-(7-HYDROXY-5-OXO-2,3-DIHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLIN-6-YL)ACETAMIDE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB1101311.gif)
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