ML-228
- CAS NO.：1357171-62-0
- Empirical Formula: C27H21N5
- Molecular Weight: 415.49
- MDL number: MFCD26792570
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-06-03 11:24:09
What is ML-228?
The Uses of ML-228
N-([1,1''-Biphenyl]-4-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine is an activator of the hypoxia inducible factor (HIF) pathway.
Definition
ChEBI: ML228 is a member of the class of 1,2,4-triazines in which the triazine ring is substituted at positions 3, 5, and 6 by pyridin-2-yl, ([biphenyl]-4-ylmethyl)amin, and methyl groups, respectively. It is an activator of the hypoxia inducible factor (HIF) pathway. It has a role as a hypoxia-inducible factor pathway activator. It is a member of biphenyls, a member of 1,2,4-triazines, a secondary amino compound and a member of pyridines.
Properties of ML-228
| Boiling point: | 686.0±65.0 °C(Predicted) |
| Density | 1.228±0.06 g/cm3(Predicted) |
| storage temp. | -20°C, Inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 2.03±0.63(Predicted) |
| color | Pale Yellow to Light Yellow |
Safety information for ML-228
Computed Descriptors for ML-228
New Products
5-bromo-4-fluoro-2-nitrobenzaldehyde (R)-(-)-2-Amino-1-propanol Cyclobutanone Fmoc-OSu 1-(2-Chloroethyl)pyrrolidine Hydrochloride 2-Amino-2-(4-methylphenyl)acetic acid β-Bromostyrene Ethyl 3-phenylpropanoate Phenethyl cinnamate Dipropyl disulfide 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran
![[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone](https://img.chemicalbook.in/CAS/20180629/GIF/1360705-96-9.gif)
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