MI-136
- CAS NO.：1628316-74-4
- Empirical Formula: C23H21F3N6S
- Molecular Weight: 470.51
- MDL number: MFCD28506294
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is MI-136?
Description
MI-136 is an inhibitor of the menin-MLL interaction (IC50 = 31 nM; Kd = 23.6 nM). By blocking MLL recruitment predominantly at the level of the menin-MLL interaction, it can inhibit androgen receptor (AR)-mediated transcription. At 40 mg/kg, MI-136 has been shown to block AR signaling, inhibiting the growth of castration-resistant tumors in mice.
Properties of MI-136
| Boiling point: | 654.9±55.0 °C(Predicted) |
| Density | 1.45±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 10 mg/ml |
| form | A crystalline solid |
| pka | 14.20±0.30(Predicted) |
| color | White to off-white |
Safety information for MI-136
Computed Descriptors for MI-136
New Products
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