metiazinic acid
- CAS NO.：13993-65-2
- Empirical Formula: C15H13NO2S
- Molecular Weight: 271.33
- MDL number: MFCD00866023
- EINECS: 2377950
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-11 19:39:08
What is metiazinic acid ?
Originator
Soripan,Specia,France,1970
Definition
ChEBI: Phenothiazine substituted at nitrogen by a methyl group and at C-2 by a carboxymethyl group.
Manufacturing Process
10-Methyl-3-acetylphenthiazine is prepared in accordance with G. Cauquil and A. Casadevall, Bull. Soc.Chim., p 768 (1955). (10-Methyl-3-phenthiazinyl)acetic acid (MP 146°C; 21.4 g) is prepared by Willgerodt's reaction (action of sulfur and morpholine, followed by hydrolysis) employing 10-methyl-3-acetylphenthiazine as starting material.
Therapeutic Function
Antiinflammatory
Trade name
Roimal (Kantoishi, Japan), Soripal (Torii, Japan).
Synthesis
Metiazinic acid is prepared via
the Willgerodt reaction (sulfur and morpholine)
from 2-acetyl-10-methylphenothiazine.
Dosage
Metiazinic acid has been beneficial to arthritis patients when given at a daily dose of 0.75 – 1.5 g/d.
Properties of metiazinic acid
| Melting point: | 146° |
| Boiling point: | 482.6±44.0 °C(Predicted) |
| Density | 1.2237 (rough estimate) |
| refractive index | 1.7500 (estimate) |
| pka | 4.12±0.10(Predicted) |
| Water Solubility | 31mg/L(30 ºC) |
Safety information for metiazinic acid
Computed Descriptors for metiazinic acid
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 5-Bromo-2-Fluoropyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4-Bromo-3-(ethoxymethyl)benzoic acid 2,4-Dichloro-5-methoxyaniline 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine N2-Isobutyryl-2'-O-methylguanosine 2-chloro-5-methylpyridin-4-amine 4-Bromobenzaldehyde 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amineRelated products of tetrahydrofuran
You may like
-
2-Bromo-4-nitropyridine-N-oxide 52092-43-0 98%View Details
52092-43-0 -
18979-61-8 98%View Details
18979-61-8 -
4, 4'-Ditolylamine (or) 4,4-Dimethyl Diphenylamine 620-93-9 98%View Details
620-93-9 -
2-Bromo-5-Chloropyridine 98%View Details
40473-01-6 -
2-Picolinic acid N-oxide 824-40-8 98%View Details
824-40-8 -
15862-34-7 5-Bromo-2-Hydroxy-3-Nitro Pyridine 98%View Details
15862-34-7 -
2-(2,4-Diaminophenoxy)ethanol Dihydrochloride 98%View Details
66422-95-5 -
Eperisone Hydrochloride APIView Details
56839-43-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.